短暂性脑缺血发作对神经保护的临床分析  

Clinical Analysis of Effect of Transient Ischemic Attack on the Nerve Protection of Subsequent Cerebral Infarction

作　　者：陈德哲[1] 赵敏[1] 王晶茹[1] 王伟伟[1] 杨霞峰[1] 

机构地区：[1]聊城市人民医院神经内科,山东聊城252000

出　　处：《中外医疗》2017年第15期70-71,77,共3页China & Foreign Medical Treatment

摘　　要：目的探讨短暂性脑缺血发作对后继脑梗死神经保护的临床分析。方法随机选取该院2014年2月—2016年1月收治的60例脑梗死患者,依据其梗死前有无短暂性脑缺血发作(TIA)的情况将其分组为A组30例(梗死前无TIA)、B组30例(梗死前有TIA),并分别于2组脑梗死患者的预后情况及B组脑梗死间隔时间、TIA持续时间、脑梗死发病频次等情况进行评价。结果 A组脑梗死患者的I级预后率为66.67%,Ⅱ级预后率为36.67%,与B组差异无统计学意义(P>0.05);且B组脑梗死患者的TIA持续≤10 min、梗死间隔时间<7 d及发作频率在2~3次的与A组差异有统计学意义(P<0.05),其I级预后效果更佳,其B组患者TIA2~3次的预后效果更佳(P<0.05)。结论其TIA状态可致使大脑产生较强耐受能力,于后继脑梗死产生神经保护,其因素与脑梗死间隔时间、发作频次及TIA持续时间具有密切关联。Objective To study the clinical analysis of effect of Transient ischemic attack on the nerve protection of subsequent cerebral infarction. Methods 60 cases of patients with cerebral infarction admitted and treated in our hospital from February 2014 to January 2016 were randomly selected and divided into two groups with 30 cases in each according to the TIA situation, the group A was without TIA before cerebral infarction and the group b was with TIA before cerebral infarction, and the prognosis of the two groups was evaluated and the cerebral infarction interval, TIA duration and incidence frequency of cerebral infarction in the group B were evaluated. Results The prognosis rate of I level and II level in the group A was respectively 66.67% and 36.67%, and the differences between the two groups was not statistically significant（P〈0.05）, and the differences in the TIA duration ≤10 min, cerebral infarction interval 7 d and attack frequency between 2and 3 between the two groups were statistically significant（P〈0.05）, and the prognosis effect in I level was better and the prognosis effect of TIA between 2 and 3 in the group B was better（P〈0.05）. Conclusion The TIA state can make the brain produce the strong tolerance and produce the nerve protection after the subsequent cerebral infarction, and the factors are closely related to the cerebral infarction interval, attack frequency and TIA duration.

关 键 词：后继脑梗死 神经保护 短暂性脑缺血 

分 类 号：R743[医药卫生—神经病学与精神病学]