宫颈癌术前新辅助介入化疗的临床疗效分析  

Analysis of clinical effect of preoperative neoadjuvant chemotherapy for cervical cancer

作　　者：苏小锋 

机构地区：[1]湛江市第二人民医院妇产科,广东湛江524013

出　　处：《泰山医学院学报》2017年第4期396-397,共2页Journal of Taishan Medical College

摘　　要：目的分析及探索术前新辅助介入化疗在宫颈癌(Ⅰb~Ⅱb期)患者治疗中的临床价值。方法收集我院收治的患宫颈癌的60例患者进行研究,随机分为两组:对照组30例直接行宫颈癌根治术治疗;研究组30例术前给予新辅助介入化疗,化疗完毕1~2周再施行手术治疗。观察及比较两组的临床疗效、手术及术后情况。结果研究组治疗的总有效率为93.33%。研究组患者的手术出血量明显少于对照组,且淋巴结阳性率、阴道切缘阳性率、宫旁累积阳性率均明显低于对照组(P<0.05)。结论术前新辅助介入化疗可减少宫颈癌患者的手术出血量,提高疗效,且安全性较高,值得进一步推广。Objective ： To analyze and probe into the the clinical value of preoperative neoadjuvant chemotherapy in the treatment of patients with cervical cancer （ stage I b - I1 b）. Methods ： 60 patients with cervical caneerand who accepted treatments in our hospital were collected as the research objects, and were randomly divided into two groups：In the control group of 30 cases, they were underwent the treatment of radical operation of cervical cancer while in the study group, 30 pa- tients were treated with neoadjuvant chemotherapy before surgery, the chemotherapy was completed for 1 - 2 weeks and then were implemented the surgical treatment. Then the clinical effect, operation and postoperative condition of the two groups were observed and eompared. Restdts： The total effective rate in the study group was 93.33%. The amount of bleeding in the study group was significantly less than that in the control group, and the positive rate of lymph nodes, the positive rate of vaginal resection margin, the cumulative positive rate of the palace was significantly lower than those in the control group （ P 〈 0.05）. Conclusion： The preoperative neoadjuvant chemotherapy can reduce the amount of bleeding in patients with cervieal cancer, improve the elinical effeet, and the safety is high,thus it is worth to be further promoted.

关 键 词：术前 新辅助介入化疗 宫颈癌 

分 类 号：R737.33[医药卫生—肿瘤]