pH值对HAPw-nmZnO-nmCaO复合生物材料形貌影响的研究  

Effect of pH Value on Morphology of HAPw-nmZnO-nmCaO Composite Materials

作　　者：孙士家 赵强[1] 袁艳波[1] 何武书[1] 张文云[1] 陈庆华[2] 苏军[1] 

机构地区：[1]昆明医科大学解放军昆明总医院临床学院口腔科,云南昆明650032 [2]昆明理工大学材料科学与工程学院,云南昆明650093

出　　处：《口腔医学研究》2017年第6期585-588,共4页Journal of Oral Science Research

基　　金：国家自然科学基金(编号:619220120058)

摘　　要：目的:探讨不同pH条件下,纳米氧化锌(nmZnO)和纳米氧化钙(nmCaO)对羟基磷灰石晶须(HAPw)表面改性形貌的影响。方法:在温度为70℃,pH分别为6.0、6.2、6.4、6.6、6.8、7.0条件下,硝酸锌和硝酸钙溶胶-凝胶法改性HAPw,通过X射线衍射仪(XRD)、透射电子显微镜(TEM)和X射线能量色散光谱仪(EDX)分析材料的物相组成和表面形貌。结果:在不同pH条件下,nmZnO和nmCaO颗粒在HAPw表面的分布存在差异。nmZnO颗粒为六方晶型,nmCaO为圆形颗粒状,颗粒与晶须通过化学键相互结合。结论:在pH为6.2和6.4时,采用溶胶-凝胶法可实现nmZnO和nmCaO对HAPw的较优改性。Objective：To investigate the effects of pH on the morphology of hydroxyapatite whisker（HAPw）modified by nano zinc oxide（nmCaO）and nano calcium oxide（nmZnO）.Methods：Under the condition of 70℃,different pH=6.0,6.2,6.4,6.6,6.8,7.0,using the zinc nitrate and calcium nitrate as the source of zinc and calcium,the hydroxyapatite whisker was modified by sol-gel method.The phase composition and surface morphology of the materials were analyzed by X ray diffraction（XRD）,transmission electron microscope（TEM）,and X ray energy dispersive spectroscopy（EDX）.Results：Under different pH conditions,the distribution of the zinc oxide and calcium oxide nanoparticles on the HAPw surface was different.The shape of nano-ZnO and nano-CaO were six crystal particle and round granular,respectively.The particles and the whiskers were bonded by chemical bonds.Conclusion：With calcium nitrate and zinc nitrate as raw materials,the hydroxyapatite whisker was modified by sol-gel method,and the optimal pH was 6.2and 6.4.

关 键 词：氧化锌 氧化钙 羟基磷灰石晶须 溶胶凝胶法 PH 

分 类 号：R783.1[医药卫生—口腔医学]