超声萃取-气相色谱/质谱法同时检测酱油中14种邻苯二甲酸酯  

Simultaneous determination of 14 phthalate esters in soy sauce by gas chromatography mass spectrometry combined with ultrasonic extraction

作　　者：杨晶[1] 张杰[1] 潘攀[2] 郭军[1] 甘虹[1] YANG Jing ZHANG Jie PAN Pan GUO Jun GAN Hong(Bengbu Medical College, Bengbu 233030, China The First Affiliated Hospital of Bengbu Medical College)

机构地区：[1]蚌埠医学院,安徽蚌埠233000 [2]蚌埠医学院第一附属医院

出　　处：《包头医学院学报》2017年第6期107-109,共3页Journal of Baotou Medical College

基　　金：安徽省高等学校自然科学研究一般项目(KJ2015B069by);蚌埠医学院院级自然科学重点项目(Byky1423zd);安徽省特色专业"预防医学"项目(皖教高[2011]5号)

摘　　要：目的:运用超声萃取-气相色谱/质谱技术,建立对酱油中的14种邻苯二甲酸酯(phthalate esters,PAEs)进行同时测定的方法。方法:采用正己烷进行超声萃取,由HP-5MS色谱柱进行分离,选择离子监测模式定性,外标法定量。结果:14种PAEs在0.1~2.0 mg/L范围内均具有较好的线性相关性,r>0.999。方法的检出限为0.15~2.65μg/kg。3个加标水平下,目标物的平均回收率在85.86%~110.17%之间,RSD(n=6)为1.63%~6.90%。结论:该方法快速简便,准确度和精密度均较高,适合酱油中14种PAEs的同时测定。Objective：To make simultaneous determination of 14 phthalate asters （PAEs） in soy sauce by gas chromatography mass spectrometry （GC/MS） com- bined with ultrasonic extraction. Method：14 Phthalate asters were extracted ultrasonically from samples by n -hexane, and separated by HP -5MS column. The iden- tification was performed in selected ion monitoring （SIM） mode and the quantification was determined by external standard method. Results： The linear dependence of 14 PAEs within 0.1 - 2.0 μg/mL was good （ r 〉 0. 999） and the detection limit was 0.15 - 2.65 μg/kg. The average recoveries of the target compounds at three added levels were between 85.86 % and 110.17 %, with relative standard deviations （ n = 6） of 1.63 % ~ 6.90 %. Conclusion： The method was simple and accu- rate, which was suitable for the simultaneous determination of 14 PAEs in soy sauce.

关 键 词：酱油 邻苯二甲酸酯 气相色谱/质谱法 塑化剂 

分 类 号：O657.63[理学—分析化学] TS264.21[理学—化学]