86例老年双相障碍患者时点应用药物的临床分析  

Clinical analysis of time-point drug use in 86 elderly patients with bipolar disorder

作　　者：王晓英[1] 衣磊[1] 

机构地区：[1]青岛市精神卫生中心心理测评室,266034

出　　处：《中国老年保健医学》2017年第3期17-18,20,共3页Chinese Journal of Geriatric Care

摘　　要：目的了解我院住院老年双相障碍患者的时点药物使用情况。方法我们以2016年10月22日在青岛市精神卫生中心住院的60岁以上老年双相障碍患者为研究对象,并对其用药情况进行调查分析。结果双相躁狂患者中以丙戊酸钠缓释片和奥氮平最为常用,使用频度分别为95.24%和61.90%;而在双相抑郁患者用以碳酸锂、丙戊酸钠缓释片和喹硫平最为常用,使用频度分别为36.51%,61.90%和60.32%。而在药物副反应方面,最常见的包括口干、恶心呕吐和便秘,发生频度分别为18.6%,17.44%和25.58%。结论我院老年双相障碍患者药物使用情况总体上比较合理,但部分患者存在用药剂量过大的特点,应引起重视,遵循个体化用药及安全用药的原则。Objectives To investigate the time-point drug use among 86 elderly patients with bipolar disorder in our hospital. Methods We choose the patients with bipolar disorder which hospitalization in Qingdao Mental Health Center on October 22,2016 as the subjects, all of them are over 60 years old. Then we investigate and anlysis the medication of the patients. Results In the drug medication of bipolar manic episode ,we use Compound Sodium Valproate and Valproic Acid Sustained Release Tablets and Olanzapine in most cases,the using frequency is 95.24% and 61.90%. In the drug medication of Bipolar depression,we use lithium and Compound Sodium Valproate and Valproic Acid Sustained Release Tablets and Quetiapine to treat the disease, the using frequency of the drugs are 36. 51% and 61.90% and 60. 32%. The most common drug adverse reaction we found is as follow：dry mouth,sickness,eoprostasis. The occur frequency of the drug adverse reaction are 18. 6% and 17.44% and 25.58% . Conclusion Generaly speaking, the medication in elderly patients with bipolar disorder in our hospital is reasonable. But the drug dosage of some patients is over average level. We should pay attontion to this question and follow the principles of individualized medication and safe medication.

关 键 词：双相情感障碍 情感稳定剂 

分 类 号：R749.4[医药卫生—神经病学与精神病学]