蜂蜜和贝复济促进唇黏膜创面愈合的疗效观察  

Effect observation of honey and rb-bFGF in promoting the wound healing of oral mucosa

作　　者：陈惠芳[1] 刘敏嘉[1] 王惠芬[2] Chen Huifang Liu Minjia Wang Huifen(Department of Ophthalmology, Shanghai Ninth People＇s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China Nursing Department, Shanghai Ninth People＇s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China)

机构地区：[1]上海交通大学医学院附属第九人民医院眼科,上海200011 [2]上海交通大学医学院附属第九人民医院护理部,上海200011

出　　处：《中华现代护理杂志》2017年第10期1380-1383,共4页Chinese Journal of Modern Nursing

基　　金：上海交通大学医学院附属第九人民医院院级护理基金项目（JYHL2013511）

摘　　要：目的 探讨蜂蜜和贝复济对口唇黏膜移植术后创面的修复治疗效果,为临床护理提供参考.方法 选取2014年1月—2015年6月笔者所在科室行口唇黏膜移植术的患者80例.采用随机数字表法随机分为4组,每组20例.对照组唇黏膜创面给予暴露清洁干燥;蜂蜜治疗组使用蜂蜜处理唇黏膜创面;贝复济凝胶组使用贝复济凝胶处理唇黏膜创面;蜂蜜加贝复济组联合使用蜂蜜和贝复济凝胶.比较4组患者的创面愈合等级、进食时间和疼痛程度.结果 术后第7天4组口唇黏膜移植术患者创面黏膜愈合程度比较,差异有统计学意义（P〈0.05）;蜂蜜加贝复济组患者创面黏膜愈合程度优于对照组和蜂蜜治疗组,差异有统计学意义（P〈0.05）.4组口唇黏膜移植术患者创面疼痛程度比较,差异有统计学意义（P〈0.05）;蜂蜜加贝复济组患者创面疼痛程度优于其他3组,差异有统计学意义（P〈0.05）.4组口唇黏膜移植术患者术后进食时间比较,差异有统计学意义（P〈0.05）;蜂蜜加贝复济组患者术后进食时间优于对照组和蜂蜜治疗组,差异有统计学意义（P〈0.05）.结论 蜂蜜和贝复济均能有效促进唇黏膜创面愈合,两者联合使用,可以缩短患者术后进食时间、减轻疼痛、促进创面愈合,进而提高患者术后生活质量.Objective To explore the efficacy of honey and recombinant bovine basic fibroblast growth factor（rb-bFGF） in promoting wound healing after the surgery of oral mucosa transplantation,and provide evidence for clinical nursing.Methods Eighty patients who underwent oral mucosa transplant surgery were selected and randomly divided into four groups by random number table method,with 20 cases in each group. Group A was the control group,the oral mucosa wounds were exposed to air and kept clean and dry;in group B, the oral mucosa wounds were treated with honey;in group C,the oral mucosa wounds were treated with rb-bFGF gel;and in Group D,the patients were treated with honey combined with rb-bFGF gel. The wound healing level, eating recovery time,and pain level of four groups were evaluated and compared.Results The comparison in wound healing degree among four groups seven days after surgery was statistically significant different （P〈0.05）;the wound healing level of group D was better than group B and C （P〈0.05）;the pain level of patients in four groups was significantly different （P〈0.05）;the pain level of group D was better than other three groups （P〈0.05）;the comparison of eating recovery time among four groups was significantly different （P〈0.05）;the eating recovery time of group D was better than group B and C （P〈0.05）.Conclusions Both honey and rb-bFGFcan effectively promote the wound healing of oral mucosa. The combination of honey and rb-bFGF,can shorten the eating recovery time,relieve pain,and promote wound healing,so as to improve patients＇ quality of life.

关 键 词：蜂蜜 贝复济 唇黏膜 创面愈合 

分 类 号：R473.6[医药卫生—护理学]