定量影像学在肺癌放/化疗疗效评估中的应用  

Quantitative Imaging Assessment of Tumor Response to Chemoradiation in Lung Cancer

作　　者：焦玉新[1,2] 任艳萍[1] 郑向鹏[1,3] 

机构地区：[1]复旦大学附属华东医院肿瘤放疗科,上海200040 [2]复旦大学附属华东医院影像科 [3]复旦大学附属华东医院张国桢肺小结节诊疗中心

出　　处：《中国肺癌杂志》2017年第6期407-414,共8页Chinese Journal of Lung Cancer

基　　金：国家自然科学基金(No.81472794);上海市科学技术委员会基金(No.124119a0400)资助~~

摘　　要：精准医疗的实施要求及时准确地对治疗疗效进行评估,以便于治疗方案的调整和优化,从而进一步提高疗效,改善预后。以定量评估为基础的影像组学以其无创、直观和可重复的特点在临床疗效评估方面具有不可替代的作用。本文将综述定量影像学在肺癌放化疗疗效评估中的应用现状及其相关进展。Precision medicine demands accurate assessment of tumor response to therapies with the purpose of timely optimization or adjustment of the given treatment regimens. Chemoradiation remains the standard of care in advanced lung cancers and imaging-based noninvasive response evaluation could improve therapeutic efficacy and reduce treatmentrelated severe side effects. In this review, we overviewed the applications and pitfalls of major imaging modalities in response evaluation in lung cancer from a quantitative perspective. The development of radiomics will provide more precise information for treatment predicting, evaluation and prognosis.

关 键 词：肺肿瘤 疗效 定量分析 影像学 

分 类 号：R734.2[医药卫生—肿瘤]