慢性阻塞性肺疾病患者焦虑、抑郁与BODE指数的相关性分析  

The relationship between anxiety and depression state and BODE index in patients with COPD

作　　者：李凡[1] 任涛[1] 程立[1] 李亚新[1] 刘彩云 

机构地区：[1]湖北医药学院附属东风总医院综合医疗科,十堰442000 [2]湖北十堰东风口腔医院

出　　处：《国际精神病学杂志》2017年第3期496-498,共3页Journal Of International Psychiatry

摘　　要：目的研究慢性阻塞性肺疾病(COPD)患者的焦虑抑郁状态、BODE指数及其相关性。方法研究对象选取我院2015年8月到2016年12月间收治的COPD患者93例,其中急性加重期COPD患者52例(AECOPD组)、稳定期COPD患者41例(SCOPD组),采用Hamilton抑郁量表(HAMD)和Hamilton焦虑量表(HAMA)评价患者抑郁和焦虑评分,同时测量BODE指数。比较两组患者的临床资料、HAMD、HAMA及BODE指数,同时比较不同BODE指数分级患者的HAMD和HAMA评分,采用Logistic多元回归分析BODE指数与HAMD和HAMA评分相关性。结果AECOPD组的HAMD、HAMA评分及BODE指数均明显高于SCOPD组(P<0.01);随着BODE指数分级增加,COPD患者的HAMD和HAMA评分均呈明显增加趋势;Logistic多元回归分析显示,HAMD和HAMA评分与BODE指数均呈明显正相关(r^2=0.56,0.53)。结论 COPD患者多伴有焦虑、抑郁情绪,且与患者BODE指数呈正相关,同时检测BODE指数可作为COPD患者病情、焦虑、抑郁程度评估指标。Objective To study the relationship among anxiety, depression and the BODE index in patients with chronic obstructive pulmonary disease （COPD） . Methods 52 patients with acute exacerbation of COPD were selected as AECOPD group, while 41 patients with stable COPD as SCOPD group. The patients in lwo group were measured hy Hamilton Depression Scale （ HAMD ）, Hamilton Anxiety Seale （ HAMA ） and BODE index. The relationship among anxiety, depression and the BODE index were analyzed. Results The score of HAMD, HAMA and BODE index in AECOPD group were significantly higher than those in SCOPD group （P 〈 0.01 ）; Logistic multivariate regression analysis showed that HAMD and HAMA scores were positively correlated with BODE index （r^2=0.56, 0.53 ） . Conclusion The anxiety and depression in COPD patients were associated with the BODE index. BODE index can be used as evalualion index for anxiely and depression in patients with COPD.

关 键 词：慢性阻塞性肺疾病(COPD) 焦虑 抑郁 BODE指数 

分 类 号：R749.23[医药卫生—神经病学与精神病学]