胃癌网膜囊筋膜微转移的研究  

Clinical Study on Bursa Omentalis and Fascia Micrometastases of Gastric Carcinoma

作　　者：李海林[1] 苏连明[2] 陈爱东[2] 张黎[3] 

机构地区：[1]牡丹江医学院红旗医院普外二科 [2]牡丹江医学院红旗医院消化内科 [3]牡丹江医学院红旗医院科研科

出　　处：《世界最新医学信息文摘》2017年第9期1-2,共2页World Latest Medicine Information Electronic Version

基　　金：黑龙江省卫计委(卫生厅)科研课题。项目基金编号2012-306

摘　　要：目的探讨胃癌病人网膜囊筋膜组织肿瘤微转移情况。方法应用RT-PCR检测CK20mRNA在100例胃癌网膜囊筋膜组织的表达。结果 100例患者网膜囊筋膜肿瘤微转移阳性率为:34%。转移与肿瘤的侵润深度、部位、病理分型、临床分期,淋巴结转移有关(P<0.05),而与患者年龄及性别无关(P>0.05)。结论 RT-PCR方法能敏感的检测胃癌网膜囊筋膜微转移。可为胃癌完整的网膜囊切除术提供可靠的理论支持。Objective To investigate the micrometastasis of omemal bursa tissue in patients with gastric cancer. Methods The measure of RT-PCR was used to detect the cytokeratin CK20mRNA and expression on micrometastases of bursa omentalis and fascia of 100 patients with gastric carcinoma, Results The positive rate ofmicrometastases ofCK20 mRNA were found in the bursa omentalis and fascia is 34%. The micrometastases has relation with depth of infiltration.location of gastric carcinoma, histologic type .lymph node metastasis （P〈0.05） ,but no relation with the age and sex of the patients （P〉0.05）. Conclusion The RT-PCR method can be used to detect the micrometastasis of the omental bursa of the stomach, which can provide a reliable theoretical support for the intact omental bursa resection.

关 键 词：胃癌 网膜囊 微转移 

分 类 号：R735.2[医药卫生—肿瘤]