窄带成像放大内镜诊断Barrett食管142例临床分析  

Clinical Analysis of 142 Patients with Barrett's Esophagus Diagnosed by Narrow Band Imaging Magnifying Endoscopy

作　　者：吴秀萍[1] 杨治中[1] 王卫芬[1] 陆盛伟 王治全[1] Wu Xiu-ping Yang Zhi-zhong Wang Wei-feng LU Sheng-wei Wang Zhi-quan(department of gastroenterology, The People＇s Hospital of Jianshui,Jianshui, Yunnan, Chin)

机构地区：[1]云南省建水县人民医院消化内科

出　　处：《世界最新医学信息文摘》2017年第10期19-21,共3页World Latest Medicine Information Electronic Version

摘　　要：目的探讨窄带成像放大内镜(NBI-ME)在诊断Barrett食管(BE)中的临床价值。方法筛选2015年3月-2016年7月我院内镜下肉眼观胃食管结合处(GEJ)近端出现桔红色柱状上皮的患者142例,分成NBI-ME组和普通内镜组,各71例,普通内镜组采用传统四象限活检法在普通内镜下对病变处进行活检;NBI组采用NBI联合放大内镜下对病变处进行靶向活检。比较两组观察病变部位的清晰度以及放大观察病变部位毛细血管结构形态的清晰度;比较两组BE活检的检出率。结果 NBI观察病变部位清晰度显著高于普通内镜,差异具有统计学意义(P<0.01);NBI放大观察病变部位毛细血管结构形态清晰度显著高于普通内镜放大(P<0.01);NBI组活检的检出率显著高于普通内镜,差异具有统计学意义(P<0.01)。结论 NBI能有效提高BE食管的检出率,NBI-ME能有效提高BE食管的病理检出率,能早期发现癌前病变;而且NBI-ME操作简单,无色素内镜的并发症,值得临床推广应用。Objective To investigate the effect of magnifying endoscopy with narrow band imaging（NBI-ME） in the diagnosis of Barrett’s esophagus（BE）. Methods：The clinical value of screening from March 2015 to July 2016 in our hospital endoscopic eye view of the gastroesophageal junction（GEJ） 142 cases of patients with proximal orange columnar epithelium, divided into NBI-ME group and ordinary Endoscopy Group, each of 71 cases, common endoscopy group using the traditional four quadrant biopsy method for biopsy of lesions in common endoscopy; group NBI with NBI combined with magnifying endoscopy for lesions of target biopsy lesions were observed and compared between the two groups. The definition and structure of capillaries observed lesion definition;comparison of detection rate of two group BE biopsy. Results NBI observation of the lesion resolution is significantly higher than that of normal endoscopy, the difference was statistically significant（P〈0.01）;NBI magnified the distinctness of the significant lesion structure of capillaries Compared with common endoscopic amplification（P〈0.01）;the detection rate of NBI group was significantly higher than that of normal endoscopic biopsy, the difference was statistically significant（P〈0.01）.Conclusion NBI can effectively improve the detection rate of BE’s esophagus, NBI-ME can effectively improve the detection rate of esophageal pathology BE, early detection of precancerous lesions;and NBI-ME has the advantages of simple operation,no chromoendoscopy complications, worthy of clinical application.

关 键 词：窄带成像 放大内镜 BARRETT食管 诊断 

分 类 号：R571[医药卫生—消化系统]