加曲班联合阿替普酶对脑梗死患者神经及认知功能的影响  

Effects of Aga-shuban combined with alteplase on neurological and cognitive function in patients with cerebral infarction

作　　者：孟杉杉[1] 

机构地区：[1]商丘市第一人民医院神内科,河南商丘476100

出　　处：《中西医结合心血管病电子杂志》2016年第34期7-7,9,共2页Cardiovascular Disease Electronic Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的探究阿加曲班联合阿替普酶对脑梗死患者神经及认知功能的影响。方法选择我院在2015年10月~2016年8月收治的脑梗死患者50例,根据随机数字表法将其分为两组。对照组患者予阿替普酶,在此基础上给予观察组阿加曲班注射液,比较两组患者认知功能和生活自理能力。结果与对照组相比,观察组患者总认知度能力及神经功能功能评分高,差异有统计学意义（P〈0.05）。结论阿加曲班联合阿替普酶能提高脑梗死患者认知功能,减少患者神经功能受损,改善生活质量。Objective To investigate the effect of argatroban and alteplase on neurological and cognitive function in patients with cerebral infarction. Methods Fifty patients with cerebral infarction were enrolled in our hospital from October 2015 to November 2016.All patients were divided into two groups according to the random number table method.The patients in the control group were treated with alteplase. On the basis of this,the observation group was treated with argatroban injection,and the cognitive function and self-care ability of the two groups were compared.Results Compared with the control group,the total cognitive ability and neurological function score of the observation group were statistically significant（P〈0.05）.Conclusion Agarotin combined with alteplase can improve the cognitive function of patients with cerebral infarction,reduce the neurological impairment and improve the quality of life.

关 键 词：阿加曲班 阿替普酶 脑梗死 神经功能 认知功能 

分 类 号：R743.3[医药卫生—神经病学与精神病学]