吲哚菁绿清除试验的临床应用  

Clinical application of indocyanine green clearance test

作　　者：王铭[1] 唐红[1] 

机构地区：[1]四川大学华西医院感染性疾病中心,成都610041

出　　处：《临床肝胆病杂志》2017年第6期1183-1187,共5页Journal of Clinical Hepatology

基　　金：四川省科技计划项目(2015SZ0049)

摘　　要：目前临床上常用的肝功能评价方法多为以血生化检测为代表的静态检测,大多侧重于检测肝脏的损伤程度及功能障碍情况,而对肝脏储备功能,即肝脏的有效功能状态的反映存在明显的局限性。吲哚菁绿(ICG)清除试验是临床中常用肝脏储备功能检测方法,且具有微创、简便、快速、可床边实时监测并短时间重复的特点。ICG清除试验在肝脏外科领域的应用价值已得到广泛认可,近年来,在肝脏内科、肝脏介入、重症患者、药物安全性评估等领域的应用研究逐步深入。现结合近几年的文献,就ICG清除试验的临床应用现状、相关进展及应用前景进行了综述。At present,the most commonly used methods for liver function evaluation in clinical practice is static detection represented by blood biochemical examinations,with a focus on the degree of liver injury and liver dysfunction; however,such methods have significant limitations on the reflection of liver reserve function. Indocyanine green（ICG） clearance test is commonly used for the testing of liver reserve function in clinical practice and it is a minimally invasive,simple,and quick procedure available for bedside real-time monitoring and can be repeated during a short period of time. The application value of ICG clearance test in the field of liver surgery has been widely recognized.In recent years,more and more studies have been focusing on the application of ICG clearance test in the fields of internal medicine,liver interventional therapy,critically ill patients,and drug safety assessment. This article reviews the current clinical application,related advances,and future perspectives of ICG clearance test.

关 键 词：肝功能试验 吲哚花青绿 综述 

分 类 号：R575[医药卫生—消化系统]