中药治疗原发性三叉神经痛的Meta分析  

Meta-analysis on TCM Treatments for Primary Trigeminal Neuralgia

作　　者：吴萍[1] 徐铭阳 张媛媛[1] 吝宇 丁德光[2] 周仲瑜[2] 

机构地区：[1]湖北中医药大学,湖北武汉430061 [2]湖北省中医院,湖北武汉430000

出　　处：《中医药学报》2017年第3期27-31,共5页Acta Chinese Medicine and Pharmacology

基　　金：国家中医药管理局中医药标准化项目-面痛病中医临床诊疗指南制定(SATCM-2015-BZ[151])

摘　　要：目的:系统评价中药治疗原发性三叉神经痛(PTN)的临床疗效及安全性。方法:计算机检索CBM、CNKI、WF、VIP、Pubmed、Cochrane Library、Embase数据库中中药治疗PTN的随机对照试验,由2名研究员独立筛选和评价文献,运用RevMan5.3软件对提取的数据进行Meta分析。结果:共纳入12篇RCTs,收治PTN患者1 015例。Meta分析结果显示,对比西药组,中药组能提高总有效率、愈显率,降低VAS评分和不良反应发生率,差异有统计学意义。结论:中药治疗PTN更为安全有效,但需更多高质量的RCTs进一步证实。Objective ： To systematically evaluate the clinical safety and efficacy of TCM treatments for primary trigeminal neuralgia（PTN）. Methods： All publications of randomized controlled trials（RCTs） studying TCM treatments for PTN were searched from CBM, CNKI, WF, VIP, Pubmed, Cochrane Library, and Embase. Two reviewers independently screened and evaluated the included articles. RevManS. 3 software was used to analyze the data. Results： 12 studies and 1015 patients were included. The meta -analysis suggests that the TCM was superior in efficacy to western medicine, being effective in reducing the score of VAS with less adverse reaction. Conclusion： TCM is a safer and more effective therapy for PTN, however, further RCTs with higher methodologies are recommended.

关 键 词：中药 原发性三叉神经痛 随机对照试验 META分析 

分 类 号：R745.11[医药卫生—神经病学与精神病学]