皮肤无针缝合器应用于腹腔镜结直肠癌切口对脂肪液化影响临床研究  

Incision suture closer without needlecan decrease incidence of incision fat liquefaction in laparoscopic operation for colorectal cancer

作　　者：苏昊[1] 周海涛[1] 周志祥[1] 梁建伟[1] 王征[1] 单毅[1] 毕建军[1] 

机构地区：[1]国家癌症中心/中国医学科学院北京协和医学院肿瘤医院结直肠外科,北京100021

出　　处：《陕西医学杂志》2017年第7期865-868,共4页Shaanxi Medical Journal

基　　金：北京市支持中央高校共建项目-青年英才计划(YETP1238);北京协和医学院院校基本科研课题(2016ZX310020)

摘　　要：目的:观察腹腔镜结直肠癌手术中,皮肤无针缝合器应用于腹壁切口缝合减少脂肪液化的效果。方法:将行腹腔镜辅助结直肠癌手术的252例患者随机分为四组,其中试验组使用皮肤无针缝合器同时皮下脂肪层不进行缝合,对照A组使用皮肤无针缝合器并采用传统皮下脂肪层间断缝合,对照B组使用皮肤钉合器同时缝合皮下脂肪层,对照C组使用皮肤钉合器同时不缝合皮下脂肪层,比较四组间伤口脂肪液化发生率。结果:试验组67例中发生切口脂肪液化1例(1.5%),对照A组62例中发生切口脂肪液化6例(9.7%),对照B组64例中发生切口脂肪液化7例(10.9%),对照C组59例中发生切口脂肪液化7例(11.9%),试验组与各对照组间切口伤口脂肪液化发生率比较均有显著统计学差异(P值分别为0.041、0.037、0.031)。结论:进行腹腔镜辅助结直肠癌手术时,不缝合皮下脂肪层,直接使用皮肤无针缝合器对合腹部切口可减少切口脂肪液化发生。Objective： To explore the application and advantage of incision suture closer without needle and non-suturing subcutaneous fat tissue in laparoscopic-assisted surgery for colorectal cancer. Methods： 252 patients with laparoscopic colorectal surgery were randomized into four groups. The trial group used incision suture closer with subcutaneous fat unsutured while the contrast group A used incision suture closer with subcutaneous fat routinely full-thickness sutured. The contrast group B and group C all used skin stapler with or without subcutaneous fat su-tured. The data of patients was collected and analyzed for assessing the impacts on wound healing by taking different types of skin suture. Results ：The trial group had only 1 incision fat liquefaction, and the contrast group A, contrast group B and contrast group C had 6 and 7 incision fat liquefaction respectively . There was significant statistic differ-ence between the trial group and all contrast groups（1. 5 % vs9. 7 % , 10. 9 % and 11. 9 % . P-value was 0. 041, 0. 037 and 0. 031 respectively）. Conclusions ：Using incision suture closer with subcutaneousfat unsutured can reduce the occurrence of fat liquefaction in laparoscopic operation for colorectal cancer.

关 键 词：结直肠肿瘤/外科学 腹腔镜检查 外科缝合器 @脂肪液化 

分 类 号：R735.3[医药卫生—肿瘤]