脉冲染料激光治疗新生儿期婴幼儿血管瘤的效果观察  

Effect of pulsed dye laser therapy on infantile hemangioma during neonatal period

作　　者：张文显[1] 杨伊帆[1] 薛磊[1] 高阳[1] 王乐[2] 曹敏娜[1] 

机构地区：[1]河北省儿童医院整形外科,河北石家庄050031 [2]河北省儿童医院儿研所,河北石家庄050031

出　　处：《河北医科大学学报》2017年第7期786-788,共3页Journal of Hebei Medical University

基　　金：河北省医学科学研究重点课题(20170408)

摘　　要：目的探讨脉冲染料激光治疗新生儿期婴幼儿血管瘤的有效性与可行性。方法应用脉冲染料激光治疗婴幼儿血管瘤患儿1 881例。依年龄划分为新生儿组(年龄≤28d)93例和非新生儿组(年龄>28d)1 788例,比较2组的临床资料。结果新生儿组临床疗效优于非新生儿组(P<0.05)。新生儿组治疗后疗效评分高于非新生儿组,单次治疗能量、总治疗能量高于非新生儿组(P<0.05)。2组总治疗次数差异无统计学意义(P>0.05)。结论特定参数的脉冲染料激光治疗新生儿期婴幼儿血管瘤是安全、有效和可行的。相较于非新生儿期的患儿,在新生儿期进行治疗效果良好。Objective To study the feasibility and validity of pulsed dye laser（PDL） for treating infantile hemangionma（IH） in neonates.Methods All patients were diagnosed as infantile hemangionmas and were divided to neonate group（younger than 28days, 93 patients） and non-neonate group（older than 28 days, 1 788 patients）.Their clinical data were collected, and the treatment outcomes and PDL parameters in neonates and non-neonates were analyzed.Results The neonates group shows a better therapy result than non-neonatal group（P〈0.05）.Laser energy used per treatment session was signifcantly lower in neonatal group than in non-neonatal group（P〈0.05）.Total laser energy used in neonates was also markedly lower than the control group（P〈0.05）.However, treatment session numbers in these two groups were no significant difference（P〈0.05）.Conclusion PDL, with distinct parameters, is a safe, feasible and effective treatment method for the therapy of IH in neonates.After each laser treatment, neonates has a better treatment result and recovered faster than non-neonatal patients.

关 键 词：血管瘤 激光 染料 婴儿 新生 

分 类 号：R732.2[医药卫生—肿瘤]