干细胞移植治疗帕金森病的进展  

Progress of Stem Cells Transplantation in the Treatment of Parkinson's Disease

作　　者：丛日博 贺娟[1] 安文瑞 赵学良[1] 王智光[1] 宝乐日[1] 

机构地区：[1]内蒙古医科大学附属医院神经内科,呼和浩特010000

出　　处：《医学综述》2017年第12期2453-2457,共5页Medical Recapitulate

摘　　要：帕金森病(PD)是一种在中枢神经系统发生的变性疾病,目前的治疗方式主要以口服药物和手术为主,但其只能短期内缓解相应症状,尚不能根除病因,达到治愈的效果。随着研究的深入,具有自我更新及分化潜能的干细胞逐渐成为研究的主题。近年来,干细胞技术得到迅猛的发展,干细胞在再生医学、建立疾病模型及药物筛选等领域逐渐显示出其巨大的应用价值。不同类型的干细胞可分化为多巴胺能神经元,因此为从根本上治愈提供了可能。Parkinson＇s disease（ PD） is a degenerative disease of the central nervous system. At present,the main treatments are drug and surgery,but they only relieve the symptoms of PD,in fact,they cannot cure the disease. With the deepening of the research,stem cells with self-renewal and differentiation potential have gradually become the subject of the study. Recently,stem cells technology has achieved rapid development,which are showing high applicative value in regenerative medicine,disease modeling and drug screening. A large number of experiments have shown that different types of stem cells can differentiate into dopaminergic neurons,so it has brought possiblity to cure PD.

关 键 词：帕金森病 干细胞移植 多巴胺 

分 类 号：R741.05[医药卫生—神经病学与精神病学]