Gleason 10分前列腺癌患者临床特点分析  

Clinical and pathological research of prostate cancer with Gleason score 10

作　　者：徐庆祝[1,2] 牛远杰[1] XU Qing-zhu NIU Yuan-jie(Department of Urology, The Second Hospital , Tianjin Medical University, Tianjin 3002112,China Department of Urology,Xianshui-gu Hospital,Jinnan District, Tianjin 300350,China)

机构地区：[1]天津医科大学第二医院泌尿外科天津市泌尿外科研究所,天津300211 [2]天津市津南区咸水沽医院泌尿外科,天津300350

出　　处：《天津医科大学学报》2017年第4期361-363,共3页Journal of Tianjin Medical University

摘　　要：目的:探讨Gleason 10分前列腺癌患者的临床病理学特点。方法:对30例临床病理资料完整的Gleason 10分前列腺癌患者的相关资料进行回顾性分析。结果:前列腺癌患者平均年龄71.9岁,组织标本病理分级均为Gleason 10分,ECT示骨转移患者10例,肺转移患者1例。血清总前列腺特异抗原平均56.35 ng/mL,平均前列腺特异抗原密度为0.57。患者体质指数(BMI)均值为23.90,大于25的患者有14位,占总数47%。结论:Gleason 10分前列腺癌患者发病年龄较大,平均血清总前列腺特异抗原水平及前列腺特异抗原密度较高,常伴有精囊侵袭、骨转移及远处转移。Objective ：To investigate the clinical and pathological features of prostate cancer patients with Gleason score 10 . Methods：Thirty cases of prostate cancer with 10 Gleason score were reviewed to analyze the clinical and pathological factors. Results：All the post-pathological results confirmed the diagnosis of prostate cancer with 10 Gleason score. The average age was 71.9, and ECT examination showed 10 patients with bone metastasis, one with lung metastasis. Mean value of total serum PSA was 56.35 ng/m and average PSAD was 0.57. Mean BMI was 23.90, but there were 14 patients with a BMI higher than 25, accounting for 47% of the total. Conclusion：The study showed that prostate cancer patients with 10 Gleason score are usually found in elder men, with higher levels of total PSA and PSAD. Simultaneously, 10 Gleason score prostate cancer patients commonly have seminal vesicles, bones and distant sites metastasis.

关 键 词：前列腺癌 GLEASON评分 临床病理特点 

分 类 号：R737.25[医药卫生—肿瘤]