直肠癌围手术期治疗研究进展  

Research progress on perioperative treatment of rectal cancer

作　　者：李飘[1] 黄婷婷[1] 刘典[1] 邱红[1] LI Piao HUANG Ting-ting LIU Dian QIU Hong(Department of Digestive Oncology, Tongji Hospital, Tongji Medical College, Huazhong Uni- versity of Science and Technology, Wuhan 430030, Chin)

机构地区：[1]华中科技大学同济医学院附属同济医院消化系统肿瘤科,湖北武汉430030

出　　处：《实用医院临床杂志》2017年第4期6-11,共6页Practical Journal of Clinical Medicine

摘　　要：目前局部晚期直肠癌推荐治疗方案是术前新辅助放化疗后全直肠系膜切除术联合术后辅助化疗。直肠癌围手术期治疗模式是一个多学科诊疗过程,涉及到同步放化疗药物的选择、术前放疗疗程长短、同步放化疗后手术的最佳时间窗选择、同步放化疗后肿瘤完全缓解者是否可避免手术、术后是否需要辅助化疗等多方面问题,其中很多问题在有初步共识的基础上仍然存在争议,有些问题仍然处于探索研究阶段。针对上述问题的细节化处理是实现直肠癌治愈目标的同时提高生活质量的保障,具有重要临床意义。Currently, the recommended treatment of locally advanced rectal cancer is preoperative neoadjuvant chemotherapy followed by total mesorectal excision and postoperative adjuvant chemotherapy. The treatment model during perioperative period in rectal cancer patients is a multidisciplinary process involving many aspects of problems that include the choice of chemo-radiotherapy drugs, the length of preoperative radiotherapy, the best time to surgical operation and whether or not to avoid surgery and adjuvant chemothera- py. Many of these problems are still controversial on the basis of preliminary consensus, and some of the problems are still in the explor- atory research phase. Dealing with these problems is to achieve the goal of rectal cancer cure and improve the quality of life that has im- portant clinical significance.

关 键 词：直肠癌 手术 放疗 化疗 

分 类 号：R735.37[医药卫生—肿瘤]