精准医学在结直肠癌诊断与治疗中的进展  

Development of precision medicine in the diagnosis and treatment of colorectal cancer

作　　者：所剑[1] 李伟[1] Suo Jian Li Wei.(Department of Gastrointestinal Surgery, the First Hospital of Jilin University, Changchun 130021, China)

机构地区：[1]吉林大学第一医院胃结直肠肛门外科,长春130021

出　　处：《中华消化外科杂志》2017年第7期657-661,共5页Chinese Journal of Digestive Surgery

基　　金：国家自然科学基金（81372295、81402374）

摘　　要：精准医学是一个以个体化治疗为基础，将基因组学、蛋白质组学、代谢组学等生物数据与临床大数据结合而发展起来的医学模式。随着精准医学时代的到来，结直肠癌的诊断与治疗也进入精准医学模式。本文就精准医学在结直肠癌诊断和治疗中的进展进行整合，旨在为临床医师和基础科研工作人员提供思路和启发，以期为结直肠癌的精准预防、精准诊断及精准治疗提供进一步支持。Precision medicine is a medical model that proposes the individual therapy, with a joint medical method of genomics, proteomics, metabolomics and clinical big data tailored to the individual patient. The diagnosis and treatment of colorectal cancer have entered the model of precision medicine with the entering the era of precision medicine. In this article, authors summarized the recent progress of diagnosis and therapy under the guidance of precision medicine, with an aim to provide some new clues for surgeons and supports for precision prevention, diagnosis and therapy.

关 键 词：结直肠肿瘤 精准医学 胃肠外科 

分 类 号：R735.34[医药卫生—肿瘤]