溴隐亭治疗中枢性高热的临床观察  

Clinical observation on the treatment of patients suffered from central high fever with bromocriptine

作　　者：史颖[1] 金鑫[1] 王德超[1] 李伟彬[1] 蔡耘[1] SHI Ying JIN Xin WANG Dechao LI Weibin CAI Yun(Department of Neurology, Affiliated Hospital of Hebei University, Baoding 071000, China)

机构地区：[1]河北大学附属医院神经内科,河北保定071000

出　　处：《医学研究与教育》2017年第3期6-9,共4页Medical Research and Education

摘　　要：目的探讨溴隐亭在重度脑血管病伴中枢性高热患者中的临床应用价值。方法前瞻性分析河北大学附属医院2014年1月至2015年12月人院的50例典型中枢性高热患者,分别采用传统退热药物联合物理降温和溴隐亭联合物理降温的治疗方案,评价不同治疗方案对降温效果、体温复燃率、治疗前后GCS评分、病死率的影响。结果溴隐亭组及对照组体温达标时间、体温复燃率差异有统计学意义(P<0.05),GCS评分、病死率差异无统计学意义(P>0.05)。结论溴隐亭可促进中枢性高热患者的体温下降速度及有效减少体温复燃,但对于患者总体预后影响甚微。Objective To explore the clinical application value of the treatment of severe cerebral vascular disease with the central high fever. Methods A retrospective analysis of 50 cases was made with typical central high fe- ver patients in our hospital from 2014 January to 2015 December. Respectively, we used traditional antipyretic drugs combined with physical cooling treatments and bromocriptine combined with physical cooling treatments, evaluated the cooling effections, temperature recrudescence rates, compared GCS scores and mortality rates be- fore and after the treatments. Results In the bromocriptine groups and control groups, there were significant differences in the temperature target times and the temperature recrudescence rates （P〈0.05）. However, there were no statistical significances between the GCS scores and mortality rates （P〉0.05）. Conclusion Bromocrip- tlne can gence of promote the temperature drop speeds in patients with central high fever and effectively reduce the resur- the temperature, but have little effect of the overall prognosis of patients.

关 键 词：中枢性高热 溴隐亭 临床观察 

分 类 号：R74[医药卫生—神经病学与精神病学]