基于掺氮碳量子点与Fe^(3+)纳米开关的抗坏血酸荧光传感器  

A fluorescence sensor for ascorbic acid based on nanocomposite "switch" of Fe^(3+) and nitrogen-doped carbon nanodots generated from chitosan

作　　者：王嘉君[1] 刘青[1] 冯施施 冯志玲 阮永明[1] 翁雪香[1] WANG Jiajun LIU Qing FENG Shishi FENG Zhiling RUAN Yongming WENG Xuexiang(College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China)

机构地区：[1]浙江师范大学化学与生命科学学院,浙江金华321004

出　　处：《浙江师范大学学报（自然科学版）》2017年第3期299-306,共8页Journal of Zhejiang Normal University:Natural Sciences

基　　金：浙江省自然科学基金资助项目(LY15C040002)

摘　　要：以壳聚糖为前驱体,在较低温度下通过水热法一步合成了掺氮碳量子点(N-FCDs),合成得到的N-FCDs具有良好的水溶性、pH稳定性及优良的荧光特性.实验表明:Fe^(3+)能猝灭N-FCDs溶液的荧光,灵敏度高且选择性好;当还原性的抗坏血酸加入荧光猝灭的Fe^(3+)-N-FCDs体系后,体系猝灭的荧光因Fe^(3+)的还原反应又得以恢复.由此,可实现对抗坏血酸的灵敏检测,检测的线性范围为1~200μmol/L,检出限为0.06μmol/L.此外,Fe^(3+)-N-FCDs的抗干扰能力强,可实现维生素C药片中抗坏血酸含量的检测,检测结果令人满意.Ascorbic acid （ AA ） was detected by using a nano-switch of ferric ions （ Fe^3＋ ）, the nitrogen-doped fluorescence carbon nanodots （N-FCDs） was synthesized by one-step hydrothermal carbonization of chitosan at a mild temperature. The as-obtained N-FCDs exhibited good water dispersibility, excellent pH stability, and strong fluorescence. The results showed that the fluorescence of the N-FCDs could be effectively quenched by Fe^3＋ and then be sensitively turned on in the presence of AA via an ＂ off-on＂ fluorescence response through the oxidation-reduction between Fe^3＋ and AA. A wide detection linear range for AA was found to be from 1μmol/L to 200 μmol/L with a detection limit of O. 06 μmol/L. The switch sensor was also successfully applied to detect vitamin C tablets with satisfactory recovery ranging from 96.9% to 106%, exhibited great opportunities for practical application in food and clinical system.

关 键 词：传感器 掺氮碳量子点 铁离子 荧光开关 抗坏血酸 

分 类 号：O657[理学—分析化学]