鼻咽癌咽后淋巴结转移的最大短径标准分析  

Analysis of nodal size criterion of retropharyngeal lymph node metastasis in nasopharyngeal cancer patients

作　　者：李贻卓[1] 李华雨[2] 秦志勇[2] 崔春艳[1] 谢传淼[1] 伍尧泮[1] 张嵘[1] 吴沛宏[1] 

机构地区：[1]中山大学附属肿瘤医院影像与微创介入中心,广东广州510060 [2]中国人民解放军第458医院放射科,广东广州510602

出　　处：《中国医学影像技术》2017年第7期989-992,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨鼻咽癌咽后淋巴结转移的最大短径诊断标准。方法回顾性分析817例初诊鼻咽癌患者的影像资料和临床资料。将有咽后淋巴结转移的患者按淋巴结的最大短径分组,分别以5mm和6mm为标准。分析以5mm和6mm为标准的2组间的总体生存率(OS),无远处转移生存率(DMFS)和无局部复发生存率(LRFS)的差异性。结果当以5mm为标准时,两组OS、DMFS、LRFS差异均无统计学意义(P均>0.05);当以6mm为标准时,OS和DMFS的差异具有统计学意义(OS:P<0.001;DMFS:P=0.001),LRFS的差异无统计学意义(P=0.380)。多因素分析显示咽后淋巴结转移的OS、DMFS、LRFS均不是鼻咽癌的独立预后因素。结论以≥6mm为诊断鼻咽癌咽后淋巴结转移的标准更为合理。Objective To explore the reasonable radiologic nodal size criterion of retropharyngeal lymph node （RLN） metastasis in patients with nasopharyngeal cancer （NPC）. Methods Imaging and clinical data of 817 NPC patients were analyzed retrospectively. The patients with RLN metastasis were classified into two groups according to the nodal size of 5 mm or 6 mm as standard in diagnosis. Overall survival （OS）, distant metastasis-free survival （DMFS） and the local-relapse-free survival （LRFS） were assessed between the two groups taking 5 mm or 6 mm as standard in diagnosis of RLN . Results No significant difference was found for OS, DMFS, LRFS between nodal size 〈5 mm group and ≥5 mm group. Difference of OS （P〈0.001）, DMFS （P=0.001） were significant statistical and difference of LRFS （P=0.380） had no significant statistical between nodal size 〈6 mm group and ≥6 mm group. OS,DMFS, LRFS were not an independent prognostic factor for NPC. Conclusion Using the minimal axial diameter of 6 mm as the nodal size criterion in diagosis of RLN metastasis in patients with NPC may be more reasonable.

关 键 词：鼻咽肿瘤 磁共振成像 淋巴结 预后 

分 类 号：R739.6[医药卫生—肿瘤] R445.2[医药卫生—临床医学]