钛种植体表面生物改性的研究进展  

Research progress in titanium dental implant biological modification

作　　者：夏一菁[1] 赵彬[1] 

机构地区：[1]山西医科大学口腔医学系,太原030001

出　　处：《中华口腔医学杂志》2017年第7期450-453,共4页Chinese Journal of Stomatology

基　　金：山西省国际科技合作项目（2014081058）

摘　　要：目前，种植体表面改性技术已基本形成较成熟的物理及化学改性体系。但钛是一种生物惰性材料，直接植入体内后不能与骨组织快速形成化学键合，可一定程度影响种植的成功率。因此，学者们在钛种植体表面引入一些可直接作用于骨细胞及周围组织的生物活性物质，通过生物活性物质的调控和促进作用，使种植体与骨组织能在短期内形成较好的骨结合。这类生物改性技术是近年种植领域的研究热点，起步较晚，目前尚未形成较完善的体系。本文对目前生物改性的主要活性物质和方法以及生物改性的研究现状及发展趋势做一综述。During the past three decades, the technology of implant surface modification has already formed well-developed methods including physical and chemical means. However, titanium is a kind of bioinert material, which will directly result in slowly bone-bond with bone tissue after implantation and ultimately reduce the success rate of dental implant surgery. Therefore, the introduction of bioactive substances which can effectively regulate and promote the proliferation of bone cells to modify the titanium implant surface has received tremendous attention in the research of oral implant field. The research of biological modification starts relatively late and it has not formed well-established system yet. The research progress is given in this paper concerning the bioactivators and methods used in biological modification. Furthermore, the current situation as well as the recent developments involving the biological modification of dental implant are also discussed in this review.

关 键 词：牙种植 钛 生物改性 

分 类 号：R783.6[医药卫生—口腔医学]