彩色多普勒闪烁伪像相关物理因素的评估分析  

Evaluation and analysis of the physical factors for the twinkling artifact: a preliminary study

作　　者：王蒙[1] 王澂[1] 张迎春[1] 李杰[2] 孙霄[2] 时丹丹[2] 商蒙蒙 宁松[2] WANG Meng WANG Cheng ZHANG Yingchun LI Jie SUN Xiao SHI Dandan SHANG Mengmeng NING Song(Ultrasonic Imaging Center, the Second Affiliated Hospital of Soochow Univesity, Suzbou 215004, Jiangsu, China Department of Ultrasound, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China)

机构地区：[1]苏州大学附属第二医院超声中心,江苏苏州215004 [2]山东大学齐鲁医院超声科,山东济南250012

出　　处：《山东大学学报（医学版）》2017年第7期110-114,123,共6页Journal of Shandong University:Health Sciences

基　　金：山东省科技发展计划(2012GSF11847);山东大学齐鲁医院科研基金资助项目;山东大学基本科研业务费专项资金(2015QLMS39)

摘　　要：目的评估超声波声学特性、结石表面形貌及机器设置条件在闪烁伪像形成中的价值。方法应用砂纸及泌尿系结石分别构建体外实验模型,砂纸模型中通过调节IU22声学功率参数(包括机械指数及声波入射角度)改变超声波特性,结石模型分别按照表面粗糙度差异进行结石分组(包括粗糙组,中度粗糙组与光滑组),然后选取两种不同机器设置条件(默认设置与优化设置)进行闪烁伪像成像,应用配对t检验分析比较砂纸模型中垂直辐射组与斜方辐射组闪烁伪像差异;应用重复测量设计的方差分析比较结石模型中不同机器设置条件下不同表面粗糙度结石组间闪烁伪像强度差异;通过线性回归分析分别对砂纸模型中机械指数、结石模型中不同结石粗糙度与闪烁伪像强度之间进行相关性分析。结果在砂纸模型中,机械指数与闪烁伪像强度存在显著正相关(r=0.938,P<0.001),斜方辐射组闪烁伪像强度较垂直辐射组明显减弱(P<0.05);泌尿系结石模型中,不同表面粗糙度泌尿系结石的闪烁伪像强度组间差异有统计学意义且其两个影响因素(表面粗糙度与机器设置条件)存在交互作用(P<0.001),相同表面粗糙度的泌尿系结石中的闪烁伪像强度在机器优化设置条件下均明显强于默认设置条件(P<0.001),而在相同机器设置条件下不同组间结石闪烁伪像强度与其表面粗糙程度呈明显正相关(r默认设置条件=0.80,r优化设置条件=0.83,P<0.001)。结论砂纸模型及泌尿系结石模型均显示闪烁伪像形成受超声波声学特性、结石表面粗糙度及机器设置条件的共同影响,了解各种相关因素的作用可提升其临床应用价值。Objective To evaluate the value of ultrasonic characteristics, the roughness of the urinary stones and ma- chine settings in the formation of the twinkling artifact. Methods Constructing the experimental model by the sandpa- per and the urinary stones respectively. In the sandpaper model part, ultrasonic output characteristics were changed by regulating the mechanical index in the IU 22 machine and the ultrasonic angle; the intensity of the twinkling artifact were compared and evaluated seperately by the correlation analysis and paired t test respectively. In the urinary stone model part, the stones were divided into the rough group, the mid-rough group and the smooth group according to the difference of the surface roughness. The display of the twinkling artifact in different groups were compared under the di- verse conditions including the default and optimized settings by repeated measures ANOVA, and the correlation analysis was performed between the twinkling artifact intensity and the roughness. Results In the sandpaper model part, the intensity of the color Doppler twinkling artifact was in obvious proportion with the mechanical index （ r = 0. 938, P 〈0.001 ）. And when the Doppler angle of the color box was tilted, the number of the color pixels in the scanning condition decreased significantly （ P 〈 0.05 ）. In the urinary stone model part, there existed significant difference among different groups and obvious interaction between the urinary stone roughness and the machine settings on the twinkling artifact intensity（ P 〈 0.001 ）. The twinkling artifact intensity was improved under the optimized machine settings com- pared with that of the default conditions in the urinary stones with the same roughness. However, under the same ma- chine settings, a direct proportion relationship was found between the twinkling artifact intensity and the urinary stone roughness with the coefficient being 0.80 and 0.83 respectively （ P 〈 0.001 ）. Conclusion Both the sandpaper phan- tom and urinary st

关 键 词：闪烁伪像 模型 评估 物理因素 

分 类 号：R574[医药卫生—消化系统]