芪凌方联合岩舒注射液治疗晚期前列腺癌的临床疗效  

Clinical Effect of Using of Chinese Herba Preparation Qiling Combined with Fu Fang Ku Shen Injection for the Patients with Advanced Prostate Cancer

作　　者：陈磊[1] 冯懿赓 郁超[1] 周智恒[1] 龚华[1] 米兰化 何晓锋[1] 孙鹏[1] 赵有康 曹宏文[1] 

机构地区：[1]上海中医药大学附属龙华医院泌尿科

出　　处：《辽宁中医杂志》2017年第7期1451-1453,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：上海中医药大学附属龙华医院第三批中青年名中医培养项目;上海市卫生和计划生育委员会中医药科研专项课题(2016JP014)

摘　　要：目的:观察并探讨通过芪凌方联合岩舒注射液治疗晚期前列腺癌(Advanced prostate cancer,APC)的临床疗效。方法:APC患者150例,完全随机分为观察组与对照组各75例。对照组患者既往给予双侧睾丸切除(手术去势)加全雄激素阻断治疗,观察组患者为对照组患者的治疗基础上另予芪凌方联合岩舒注射液治疗。记录两组患者治疗前后的前列腺特异抗原(prostate specific antigen,PSA),KPS评分,最大尿流速及前列腺体积,统计其治疗后的并发症发生情况以及总体疗效。结果:除两组患者的前列腺体积大小无明显差异(P>0.05),观察组的各项观察指标均优于对照组(P<0.05)。结论:芪凌方联合岩舒注射液治疗可以改善APC患者病情,提高患者生存质量,在临床上值得推广应用。Objective：To observe and explore the clinical value of using of chinese herba preparation Qiling combined with FuFang Ku Shen Injection for the patients with advanced prostate cancer.Methods：150 patients with advanced prostate cancer（APC）in urology department of longhua hospital since August 2015 to February 2017 were selected as the observation group in this study,Were randomly divided into two groups and the control group,75 cases.The control group were treated with conventional bilateral orchiectomy and maximal androgen blockade,while the observation group were treated with chinese herba preparation Qiling combined with Fu Fang Ku Shen Injection On the basis of the control group.The prostate specific antigen（PSA）,maximum urinary flow rate,prostate volume and KPS score before and after the treatment in two groups were recorded for statistical analysis,while the complications and overall efficacy were also compared.Results：Except for the prostate volume of the two groups,there was no significant difference（P〉0.05）.The observation indexes of the observation group were better than those of the control group（P〈0.05）.Conclusion：Using of chinese herba preparation Qiling combined with Fu Fang Ku Shen Injection has a significant effect and significantly improve the condition and quality of life for the patients with APC,thus it＇s worth popularization and application in clinic.

关 键 词：芪凌方 岩舒注射液 晚期前列腺癌 临床疗效 

分 类 号：R737.25[医药卫生—肿瘤]