国内不同人群对粪菌移植的态度调查  

A survey of Chinese different populations' views on fecal microbiota transplantation(FMT)

作　　者：韩忠政 李佩[1] 陈钟[1] 关富[1] 张鸣青[1] 

机构地区：[1]厦门大学附属东南医院(解放军第175医院)消化内科,漳州363000

出　　处：《东南国防医药》2017年第3期225-230,共6页Military Medical Journal of Southeast China

基　　金：吴阶平医学基金会临床科研专项资助项目(320.6750.15231)

摘　　要：目的了解我国不同人群对粪菌移植这一新疗法的接受程度及担忧问题。方法本次调查共设计了11道关于类菌移植的问题。调查方式包括通过QQ、微信两大社交平台进行网络调查和在厦门大学附属东南医院门诊及住院处进行直接调查。结果本次调查共统计了428名参与者,包括100名医务人员、114名肠道疾病患者、82名患者家属及132名健康者。当他们患有肠道疾病时,71.26%参与者愿意将粪菌移植作为一种治疗方案,并且男性人数多于女性(76.11%vs65.84%,P=0.019)。关于粪便供体的选取,57.94%参与者更愿意选择亲属作为供体,41.36%参与者会听取医师的推荐。选择粪菌移植的原因,69.86%参与者认为是由于传统药物治疗失败。结论当患有肠道疾病时,多数人愿意去了解粪菌移植并接受其作为治疗方案。传统药物治疗失败及医师的推荐是人们选择粪菌移植的两个主要原因。感染到其他疾病则是人们对粪菌移植的最大担忧。Objective To learn about the acceptability and concerns about FMT from Chinese different populations.Methods This questionnaire survey consists of 11 questions about FMT. We conducted a survey using social networks including QQ and Wechat and directly inquiring some people who are in outpatient clinic and hospitalized at the 175 th Hospital of PLA.Results For this study,428 individuals were surveyed including 100 medical staff,114 patients,82 family members of patients and132 other healthy public. If they live with those intestinal diseases,71.26% would be willing to undergo FMT as a treatment,and male participants were more likely to undergo FMT than female,76.11% versus 65.84%（ P = 0.019）. For donor selection,57.94% of subjects preferred to have a family member as their fecal donor and 41.36% preferred whomever their doctor recommended. For some factors in considering FMT,69.86% participants chose failure of conventional medications as an important factor. Conclusion In this survey,the large majority of participants were interested in or willing to consider FMT when they lived with those intestinal diseases.Failure of conventional medications and effectiveness and safety reportedly,were the two most important factors in considering FMT.The possibility of infecting with other diseases was key issues in considering FMT.

关 键 词：不同人群 粪菌移植 看法 问卷调查 

分 类 号：R574[医药卫生—消化系统]