不同放疗剂量同期化疗治疗不能手术食管癌的临床效果  

Clinical Outcome of Concurrent Chemoradiotherapy with Different Radiotherapy Dosage for Esophageal Cancer

作　　者：院刚[1] 郝灵芳[1] YUAN Gang HAO Ling-fang(The first hospital of lnner Mongolia Hohhot, Hohhot in Ilnner Mongolia 010030)

机构地区：[1]内蒙古呼和浩特市第一医院,内蒙古呼和浩特010030

出　　处：《世界最新医学信息文摘》2017年第14期4-5,共2页World Latest Medicine Information Electronic Version

摘　　要：目的探讨不同放疗剂量同期化疗治疗不能手术食管癌的效果。方法回顾性总结我院2012年5月至2014年5月年收治的不能手术的60例食管癌患者,根据放疗剂量的差异,将其分为A组(高剂量组;33例)与B组(低剂量组;27例)。观察两组临床效果。结果两组总有效率、两年生存率差异无统计学意义(P>0.05);A组毒副反应发生率明显高于B组,差异有统计学意义(P<0.05)。结论低剂量放疗同期化疗方法与高剂量放疗的疗效基本一致,可有效治疗食管癌,防止病情的恶化,且其毒副反应较少,值得临床中推广应用。Objective To investigate the effect of different doses of radiotherapy in the treatment of esophageal cancer with unresectable. Methods We choosed 60 patients with esophageal cancer who were admitted to our hospital from May 2012 to May 2014. The patients were divided into group A（high dose group, n = 33） and group B（low dose group, n = 27） according to the difference of radiotherapy dose. comparing the clinical effects of two groups. Results There was no significant difference in the total effective rate and the 2-year survival rate between the two groups（P〉0.05）. The side effects incidence of group A was significantly higher than group B, the difference was statistically significant（P〈0.05）. Conclusion The curative effect between low dose radiotherapy and high dose radiotherapy is the same, which can effectively treat esophageal cancer, prevent the deterioration of the disease, and has less side effects, it is worthy of clinical application.

关 键 词：食管癌 放疗剂量 同期化疗 临床效果 

分 类 号：R735.1[医药卫生—肿瘤]