PET/CT在肝细胞癌中的临床应用及进展  

Clinical application of positron emission tomography/computed tomography in hepatocellular carcinoma and related research advances

作　　者：章泽宇 程红岩[1] ZHANG Zeyu CHENG Hongyan.(Department of Nuclear Medicine, Eastern Hepatobiliary Surgery Hospital, Second Military Medical Univer- sity, Shanghai 201805, China)

机构地区：[1]第二军医大学附属东方肝胆外科医院核医学科,上海201805

出　　处：《临床肝胆病杂志》2017年第7期1365-1368,共4页Journal of Clinical Hepatology

摘　　要：肝细胞癌病死率很高,常规诊断发现时患者多为中晚期。PET/CT作为分子影像的方法之一,已显现出越来越重要的作用。然而,其也具有一定的局限性,如对高分化肝细胞癌及小肝癌的诊断多为假阴性。因此联合应用多种示踪剂可以提高PET/CT显像对肝细胞癌诊断的灵敏度和特异度。对PET/CT在肝细胞癌的疗效评估、复发监测及预后方面的研究进展进行了介绍。Hepatocellular carcinoma（HCC） has a high fatality rate and most patients are in advanced stage when diagnosed with routine methods.As a molecular imaging method,positron emission tomography/computed tomography（PET/CT） has become more and more important.However,it also has certain limitations,since it always has false-negative results for well-differentiated HCC and small HCC.Therefore,a combination of various tracers can improve the sensitivity and specificity of PET/CT in the diagnosis of HCC.This article reviews the role of PET/CT in the therapeutic effect evaluation,recurrence monitoring,and prognosis of HCC.

关 键 词：癌 肝细胞 放射性示踪剂 体层摄影术 综述 

分 类 号：R735.7[医药卫生—肿瘤]