认知功能评估与CT成像在轻度认知障碍中的应用  

Application of Evaluation of Cognitive Function and CT Imaging in Mild Cognitive Impairment

作　　者：许伟杰[1] 黎艳[2] 莫新[3] 陈文胜[1] 区汝飞[1] 李文轩[1] XU Wei-iie LI Yan Mo Xin et al(Department of Radiology, the Third People＇s Hospital of Foshan, Foshan 528000, Guangdong Province, Chin)

机构地区：[1]广东省佛山市第三人民医院放射科 [2]广东省佛山市第三人民医院老年科 [3]广东省佛山市第三人民医院神经内科,广东佛山528000

出　　处：《罕少疾病杂志》2017年第4期25-26,共2页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨认知功能评估与CT成像在轻度认知障碍中的应用。方法采用简单智能状态检查量表(MMSE)和蒙特利尔认知评估量表(Mo CA)对50例轻度认知障碍患者(MCI组)和50例同期正常老年体检者(对照组),行认知功能评估,进行CT成像检测并计算海马指数。结果对照组和MCI组之间Mo CA评分和MMSE评分差异具有统计学意义(P<0.05),MCI组海马指数与颞角宽度和对照组比较差异均有统计学意义(P<0.05)。结论采用认知功能评估与CT联合检测轻度认知障碍更加快速、准确,为临床预防与治疗提供更为客观的指标。To discuss the application of cognitive function evaluation and CT imaging in mild cognitive impairment. Methods A total of 50 patients with mild cognitive impairment （MCI group） and 50 elderly who had normal physical examination （control group） were evaluated cognitive function by Mini-mental State Examination （MMSE） and Montreal cognitive assessment （MoCA）. CT imaging of each group were performed to detect and the hippocampal index was calculated. Results The difference between MoCA score and MMSE score of MCI group and control group had statistical significance （P〈0.05）. Compared with the control group, the scores of each cognitive domain in MCI group were decreased, which were statistically significant （P〈0.05）. The difference between the hippocampal index and the width of temporal horns in both groups had statistical significance （P〈0.05）. Conclusion To detect mild cognitive impairment, combining the evaluation of cognitive function and CT imaging is rapider and more accurate, which provides objective indicators for clinical prevention and treatment.

关 键 词：认知功能评估 轻度认知障碍 CT 阿尔茨海默病 

分 类 号：R749.16[医药卫生—神经病学与精神病学]