磁共振扩散张量成像在急性脑梗死的诊断及运动功能评估中的应用价值  

The Application Value of Diffusion Tensor Imaging in Acute Cerebral Infarction and Motor Function Evaluation

作　　者：梁海毛[1] 谢金华 蓝宇[1] 宋志彬[1] 朱峰正[1] 景举珍[1] 董延江[1] 陈其锋[1] 

机构地区：[1]南方医科大学附属小榄医院放射科,广东中山528415 [2]广东省中山市东凤人民医院放射科,广东中山528425

出　　处：《中国CT和MRI杂志》2017年第8期47-49,共3页Chinese Journal of CT and MRI

基　　金：中山市科研基金立项(项目编号:20113A092)

摘　　要：目的探讨磁共振扩散张量成像(DTI)在急性脑梗死患者的诊断及运动功能评估的价值。方法分析49例不同时间窗的急性脑梗塞病人的MRI影像资料,所有病人均行常规MRI、DWI及DTT扫描,测量FA值、ADC值,DTT评估梗死灶与皮质脊髓束的关系。结果梗死不同时期,随着时间的推移FA值呈降低趋势,ADC值呈逐渐升高趋势。超急性期、急性期病灶中心区与边缘带的FA值及ADC值差异有统计学意义。根据弥散张量纤维束(DTT)成像梗死灶与皮质脊髓束关系分为不累及、受压无中断、破坏中断减少,破坏组及受压组的FA值、ADC及NIHSS评分差异具有统计学意义。结论磁共振扩散张量成像在急性脑梗死中FA及ADC值具有特征性演变规律,可评估急性脑梗死缺血半暗带情况,DTT可以显示梗死灶对皮质脊髓束的影响,有利于评估预后。Objective To investigate the value of diffusion tensor imaging in acute cerebral infarctiou and motor function evaluation. Methods MRI features were aualyzed in 49 patients in acute cerebral infarction with different tinting. All patients underwent conventional MRI, DWI and DTT scanning. The FA value and ADC value were measured and reconstruct the corticospinal tract by DTT.Results In acute cerebral infarction, FA value continued to decline after the oneset of attack, and ADC wdue showed an upward trend. Difference of FA value and ADC value between tbe central and peripheral regions were significant in hyperacute and acute stroke. According to diffusion tensor fiber tractography （DTT） and based on the relationship between infarction and corticospinal tract, divided into not compression, compression without interruption（the compression group）, disruption and decreases（the destruction groups）.There has statically significant difference between two groups in FA, ADC value and NIHSS score.Conclusion Magnetic resonance diffusion tensor imaging in the acute cerebral infarction with FA and ADC value have characteristic discipline, can be assessed the ischemic penumbra. DTT can show the relationship between infarction and corticospinal tract has importaut value to prognosis.

关 键 词：脑梗塞 磁共振成像 扩散张量成像 扩散张量纤维束成像 

分 类 号：R74[医药卫生—神经病学与精神病学] R44[医药卫生—临床医学]