Littoral-cell angioma of the spleen:a case report  

作　　者：Dongming Liu Zhaohui Chen Tongtong Wang Baichang Zhang Hongyuan Zhou Qiang Li 

机构地区：[1]Department of Hepatobiliary Oncology,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Key Laboratory of Cancer Prevention and Therapy

出　　处：《Cancer Biology & Medicine》2017年第2期194-195,共2页癌症生物学与医学（英文版）

摘　　要：Littoral-cell angioma(LCA), a primary angioma which clinically belongs to splenic hemangioma, can be mostly found in normal spleen red sinus shore cells of reticuloendothelial cell system. The cells of LCA strongly express endothelial and tissue cell associated antigens that indicate a dual differentiation characteristic; whereas only endothelial cell markers are positive in normal spleen red sinus shore cells. Diagnosis of LCA relies on histopathology. Regular follow-up is needed to monitor recurrence and metastasis.Littoral-cell angioma（LCA）, a primary angioma which clinically belongs to splenic hemangioma, can be mostly found in normal spleen red sinus shore cells of reticuloendothelial cell system. The cells of LCA strongly express endothelial and tissue cell associated antigens that indicate a dual differentiation characteristic; whereas only endothelial cell markers are positive in normal spleen red sinus shore cells. Diagnosis of LCA relies on histopathology. Regular follow-up is needed to monitor recurrence and metastasis.

关 键 词：Splenic hemangioma case report spleen red sinus shore cells 

分 类 号：R733.2[医药卫生—肿瘤]