高原地区颅内血管密度增高病因分析  

Analysis of the causes of increase intracranial vascular density in people living at plateau area

作　　者：曹成瑛 陈红 马院林 张海青 

机构地区：[1]青海省心脑血管病专科医院放射科,西宁810012

出　　处：《放射学实践》2017年第7期683-686,共4页Radiologic Practice

摘　　要：目的:探索高原地区患者颅脑CT平扫显示血管密度增高的病因,分析其与血红蛋白浓度的相关性。方法:搜集居住在海拔2500~4800m的186例颅内血管密度增高患者的病例资料作为研究组,另选取98例颅脑CT正常的成人为对照组。分析所有患者临床特点,统计各种病因所占比例,比较两组颅内动脉、静脉窦CT值、近期血红蛋白含量的差异并进行统计学分析。结果:186例高原地区颅内血管CT值增高患者中,慢性阻塞性肺病(COPD)134例,占72.0%,慢性高原病(CMS)46例,占24.7%,右向左分流型先天性心脏病(CHD)6例,占3.2%。与对照组相比,研究组血红蛋白含量、脑动脉、静脉窦CT值均增高,差异具有统计学意义(F=720.781、150.952、221.988,P<0.01)。颅内血管密度增高组脑动脉CT值与血红蛋白含量呈正相关(b=0.202、0.271、0.292,P<0.05)。结论:高原地区颅内血管密度增高及程度与血红蛋白含量呈正相关,高原地区引起血红蛋白浓度增高的病变都可能使脑血管密度增高。Objective： To investigate the main causes of increase intracranial vascular density displayed on head CT scan in people living at plateau area,and to analyze the relationship between increase intracranial vascular density and hae- moglobin concentration. Methods： 186 cases who live at plateau area with 2500-4800m above sea level with increase intracranial vascular density on head CT （study group） and 98 healthy subjects with normal head CT （control group） were collected. The clinical characteristics and the proportion of various diseases were counted. The difference of study group and control group in intracranial artery and venous sinus CT value, recent hemoglobin concentration were analyzed. Results： Of the 186 cases in study group with increase CT value in intracranial blood vessels, there were 134 cases （72.0 % ） with chron ic obstructive pulmonary disease,46 cases （24.7%） with chronic mountain sickness 6 cases （3.2%） with cyanotic right-to- left shunt congenital heart disease. Compared with the control group,the hemoglobin content, cerebral artery and venous si nus CT values of study group increased,with significant difference （F measure=720. 781,150. 952,221. 988,P〈0. 01）. Cerebral vascular CT value was positively correlated with the hemoglobin concentration （b = 0. 202,0. 271,0. 292, P〈C 0.05）. Conclusion： There was a positive correlation between the degree of increase intracranial vascular density and the concentration of hemoglobin in people living at plateau area,all of the diseases which can cause increase hemoglobin concentra- tion might cause increase cerebral vascular density.

关 键 词：体层摄影术 X线计算机 颅脑血管 血红蛋白 慢性阻塞性肺病 慢性高原病 先天性心脏病 

分 类 号：R743[医药卫生—神经病学与精神病学] R816.1[医药卫生—临床医学]