激光针治疗乳腺癌相关淋巴水肿的临床研究  

Clinical effects of laser acupuncture treatment on breast cancer-related lymphoedema

作　　者：金明子[1] 周愉[1] 曹红平[2] 张海蒙[2] 

机构地区：[1]上海中医药大学国际教育学院,上海201203 [2]上海中医药大学针灸推拿学院,上海201203

出　　处：《中国医药导报》2017年第20期101-104,共4页China Medical Herald

基　　金：国家自然科学基金青年基金项目(81303032);国家自然科学基金重大国际合作研究项目(81320108028)

摘　　要：目的观察He-Ne激光针治疗乳腺癌相关淋巴水肿(BCRL)的临床效果及安全性。方法选择2014年11月~2016年3月上海复旦大学附属华山医院分院收治的BCRL患者32例,按随机数字表分为治疗组和对照组,每组各16例,治疗组在对照组常规治疗基础上,选取10个穴位,进行He-Ne激光针治疗,每次同时照射2个穴位,每个穴位照射5 min,单次治疗时间共25 min,每周治疗2次,连续治疗6周,共治疗12次。比较两组治疗前后、治疗结束后4周随访时,患肢臂围变化及患肢水肿改善率,观察患者不良反应情况。结果 (1)治疗组治疗后与治疗前比较,患肢臂围显著减小(症状减轻),差异有统计学意义(P<0.05),治疗结束后4周随访时与治疗前比较,患肢臂围持续减小,差异有统计学意义(P<0.05)。对照组入组6、10周后与入组前比较,患肢臂围有增大的趋势(症状加重),但差异无统计学意义(P>0.05)。(2)治疗6周,治疗组患肢水肿改善率显著高于对照组,差异有统计学意义(P<0.05);治疗结束后4周随访,治疗组患肢水肿改善率显著高于对照组,差异有统计学意义(P<0.05)。(3)在治疗及随访期间无不良反应报告。结论 He-Ne激光针可以有效改善BCRL患者的水肿程度,并具有良好的安全性。Objective To observe the clinical effects and safety of laser acupuncture treatment on breast cancer-related lymphoedema（BCRL）. Methods From November 2014 to March 2016, in Branch Courts of Huashan Hospital of Shanghai Fudan University, 32 BCRL patients were selected, according to random number table, they were divided into treatment group and control group, with 16 cases in each group. On the basis of conventional treatment（control group）, the treatment group was given He-Ne laser acupuncture treatment on 10 selected acupuncture points. The 10 points were paired off and radiated for 25 min in a single treatment, 5 min per pair. The whole therapy lasted for six weeks, twice a week,adding up to a total of 12 times. The patients＇ affected arms were measured before treatment and after treatment, and also at 4th week follow-up after treatment finished. Data of two groups were compared and arm edema changes were recorded.Adverse reactions were observed all along. Results（1）In treatment group, the patients＇ affected arm circumference be fore treatment was compared with after 6 weeks of treatment, their arm circumference decreased（symptoms relieved）, the difference was statistically significant（P 0.05）, 4 weeks after the treatment ended, their arm circumference had kept decreasing, the differences were statistically significant（P 0.05）. In control group, the figures at baseline and 6th, 10 th week after they joined were compared with before they joined, their arm circumference increasing tendency（symptoms aggravated）, but the difference was not statistically significant（P 0.05）.（2）After 6 weeks of treatment, the improvement rate in treatment group was more than control group, the dif ference was statistically significant（P 0.05）; 4weeks after the treatment ended, the follow-up examination, the improvement rate in treatment group was more than control group, the difference was statistically significant（P 0.05）.（3） No adverse reaction reported during treatment and follow

关 键 词：乳腺癌 淋巴水肿 激光针 临床疗效 

分 类 号：R737.9[医药卫生—肿瘤]