CO_2激光与等离子两种方法治疗喉乳头状瘤的疗效对比  

Comparative study on Therapeutic Effectiveness of CO_2 Laser and Low-temperature Plasma on Laryngeal Papilloma

作　　者：魏锐文[1] 范敏 崔榕[1] 蒋锐明[1] 蒋亚林[1] 

机构地区：[1]成都市第七人民医院,四川成都610021 [2]成都市第十人民医院,四川成都610061

出　　处：《四川医学》2017年第7期787-790,共4页Sichuan Medical Journal

摘　　要：目的评估两种方法治疗喉乳头状瘤的疗效及安全性。方法随机将63喉乳头状瘤患者分为两组,A组采用显微镜下CO_2激光切除,B组采用7070号低温等离子射频刀头切除。比较两组患者的声带粘连、术后复发及恶变情况。结果 CO_2激光治疗组较等离子治疗组复发率低,差异有统计学意义(P=0.027);对单发病灶患者,CO_2激光治疗组较等离子治疗组复发率低,差异有统计学意义(P=0.040);对多发病灶患者,CO_2激光治疗组与等离子治疗组复发率比较,差异无统计学意义(P=0.395);CO_2激光治疗组较等离子治疗组声带粘连发生率低,差异有统计学意义(P=0.027)。复发主要发生在术后12个月以内,尤其是术后6个月。结论 CO_2激光治疗喉乳头状瘤安全、有效,并发症少。Objective To evaluate the efficacy and safety of CO2 laser and low-temperature plasma. Methods 63 pa- tients with laryngeal papilloma were randomly divided into two groups. A group was treated with CO2 laser under microscope while B group was treated with CoblatorTM Reflex#7070. Vocal cord adhesion, postoperative recurrence and malignant transformation of two groups were compared. Results CO 2 laser group had a lower rate of recurrence than low-temperature plasma group （P = 0. 027）. For patients with single lesion, CO 2 laser group had a lower rate of recurrence than low-temperature plasma group （P = 0. 040）. For patients with multiply lesions, there were no statistical differences between two groups （ P = 0. 395 ）. Compared with low-temperature plasma group, the incidence of vocal cord adhesion in CO2 laser group was lower （P = 0. 027 ）. The recurrence mainly happened within 12 months after operation,especially within 6 months after operation. Conclusion CO2 laser is safe and efficient and causes few complications in the treatment of laryngeal papilloma.

关 键 词：喉乳头状瘤 CO2激光 低温等离子 

分 类 号：R739.65[医药卫生—肿瘤]