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机构地区:[1]哈尔滨医科大学附属第一医院胰胆外科,150001
出 处:《中华肝胆外科杂志》2017年第7期499-502,共4页Chinese Journal of Hepatobiliary Surgery
基 金:国家自然科学基金(81100314,81370565);黑龙江省新世纪优秀人才培养计划(1253-NCET-017);哈尔滨医科大学于维汉院士杰出青年基金
摘 要:肥胖是急性胰腺炎(AP)发病的独立危险因素。肥胖者较非肥胖者AP的发病风险及其严重程度均明显增加。然而,脂肪组织(AT)在急性胰腺炎发生发展中的作用机制至今尚未完全阐明。近年来,这一问题逐渐引起国内外学者的广泛关注。本文对AT在AP中的作用研究做一综述,以期为AP发病机制的深入理解和新的治疗靶点的提出提供参考。Obesity is an independent risk factor for acute pancreatitis (AP), and the morbidity risk and severity of AP in obese patients were significantly increased than those in non-obese patients. However, the exact mechanism has not been fully elucidated. In recent years, the researches on the role of adipose tissue (AT) in AP have gradually attracted wide attention of scholars both at home and abroad. To better understand the pathogenesis and new therapeutic targets of AP, in this paper, we overviewed the recent research progress on the role of AT in AP.
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