Early prevention of trauma-related infection/sepsis  

作　　者：Xiao-Yuan Ma Li-Xing Tian Hua-Ping Liang 

机构地区：[1]State Key Laboratory of Trauma,Burns and Combined Injury,Research Institute of Surgery,Daping Hospital,Third Military Medical University

出　　处：《Military Medical Research》2017年第2期101-108,共8页军事医学研究（英文版）

基　　金：supported by grants from the National Basic Research Program of China(973 Program)(No.2012CB518102);the key project of "Twelfth Five-Year" plan for medical science and technology of PLA(No.BWS11J038);the special fund of PLA(2014ZX09J14107-08C)

摘　　要：Trauma still represents one of the major causes of death worldwide. Despite the reduction of post-traumatic sepsis over the past two decades, the mortality of septic trauma inpatients is still high(19.5%–23.0%). Early prevention of sepsis development can aid in the subsequent treatment of patients and help improve their outcomes. To date, the prevention of trauma-related infection/sepsis has mainly included infection prevention(e.g., surgical management, prophylactic antibiotics, tetanus vaccination, immunomodulatory interventions) and organ dysfunction prevention(e.g., pharmaceuticals, temporary intravascular shunts, lung-protective strategies, enteral immunonutrition, acupuncture). Overall, more efficient ways should be developed to prevent trauma-related infection/sepsis.Trauma still represents one of the major causes of death worldwide. Despite the reduction of post-traumatic sepsis over the past two decades, the mortality of septic trauma inpatients is still high（19.5%–23.0%）. Early prevention of sepsis development can aid in the subsequent treatment of patients and help improve their outcomes. To date, the prevention of trauma-related infection/sepsis has mainly included infection prevention（e.g., surgical management, prophylactic antibiotics, tetanus vaccination, immunomodulatory interventions） and organ dysfunction prevention（e.g., pharmaceuticals, temporary intravascular shunts, lung-protective strategies, enteral immunonutrition, acupuncture）. Overall, more efficient ways should be developed to prevent trauma-related infection/sepsis.

关 键 词：PREVENTION TRAUMA INFECTION SEPSIS 

分 类 号：R641[医药卫生—外科学]