凉血止痢汤与锡类散保留灌肠治疗溃疡性结肠炎的疗效对比  

Comparison of Liangxue Zhili Soup and Tin Powder with Retention Enema in the Treatment of Ulcerative Colitis

作　　者：易满[1] 刘金辉[2] 黄凤[1] 王军省[1] 潘芳杰[1] 

机构地区：[1]新疆医科大学附属中医医院肛肠一科,新疆乌鲁木齐830000 [2]新疆医科大学附属中医医院康复科,新疆乌鲁木齐830000

出　　处：《现代生物医学进展》2017年第21期4132-4134,4099,共4页Progress in Modern Biomedicine

摘　　要：目的:观察凉血止痢汤与锡类散保留灌肠治疗溃疡性结肠炎的疗效。方法:选取80例溃疡性结肠炎患者,按随机数字表法分为两组,对照组(39例)给予锡类散治疗,观察组给予凉血止痢汤治疗,观察两组治疗后的疗效,腹痛、腹泻、脓血便消失时间,治疗前后C反应蛋白、白细胞、血红蛋白数目及治疗期间不良反应情况。结果:治疗后,两组治疗有效率比较无明显差别(P>0.05),观察组患者腹痛、腹泻、脓血便消失时间均短于对照组(P<0.05),两组组白细胞数目、C反应蛋白水平均较治疗前显著下降且观察组上述指标较对照组更低(P<0.05)。两组血红蛋白数目均较治疗前显著上升且观察组较对照组更高(P<0.05)。两组治疗期间均无肝肾功能异常、胃肠道异常等不良反应发生。结论:凉血止痢汤与锡类散联合对溃疡性结肠炎均具有较好的治疗效果,能更快消退溃疡性结肠炎症状,且安全性高。Objective：To compare Liangxue Zhili Soup and Tin powder with retention edema in the treatment of ulcerative colitis.Methods：80 patients with ulcerative colitis were selected and randomly divided into two groups.The control group （39 cases） was given Tin pounder.The observation group （41 cases） was given Liangxue Zhili Soup,the efficacy,disappeared time of abdominal pain,diarrhea,blood and pus stool,C reactive protein,white blood cells,hemoglobin and adverse reactions during the treatment were observed and compared between two groups.Results：After treatment,there was no statistical significance in the effective rate between two groups （P〉0.05）.The disappeared time of abdominal pain,diarrhea,blood and pus stool of observation group were shorter than those of the control group （P〈0.05）.The white blood cells,C reactive protein were decreased in both groups.These indexes of observation group were lower than those of the control group （P〈0.05）.The hemoglobin levels were increased in two groups and was higher in the observation group than that of the control group （P〈0.05）.During treatment,there was no liver and kidney dysfunction,gastrointestinal abnormalities occurred in two groups.Conclusion：Liangxue Zhili Soup and Tin powder had good therapeutic effect on ulcerative colitis,which could vanish the symptoms of ulcerative colitis fast with high safety.

关 键 词：凉血止痢汤 锡类散 中药保留灌肠 溃疡性结肠炎 

分 类 号：R574.62[医药卫生—消化系统]