珍珠明目滴眼液联合抗生素治疗慢性结膜炎的临床观察  

Clinical effects of Zhenzhumingmu eye drops combing with antibiotic in treatment of chronic conjunctivitis

作　　者：顾燕萍 王晓燕 

机构地区：[1]浙江省绍兴市上虞妇幼保健院药剂科

出　　处：《中国生化药物杂志》2017年第7期109-110,113,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的观察珍珠明目滴眼液联合抗生素治疗慢性结膜炎的临床疗效。方法以2015年1月~2016年10月期间浙江省绍兴市上虞妇幼保健院眼科收治的96例慢性结膜炎患者为对象进行分析,抽签法进行分组,各48例。对照组给予氧氟沙星滴眼液进行治疗,观察组在此基础上加用珍珠明目滴眼液。分析2组的疗效,主要症状改善,以及不良反应情况。结果 （1）观察组总有效率为87.50%,高于对照组66.67%（P〈0.05）。（2）治疗后,观察组眼干、眼痒、眼疲劳和异物感症状得分分别为（1.01±0.24）、（0.93±0.22）、（0.85±0.18）、（0.81±0.25）分,均低于对照组（1.46±0.30）、（1.39±0.25）、（1.16±0.21）、（1.22±0.29）（均P〈0.05）。（3）观察组在用药期间有6例（12.50%）患者出现眼部不适感,高于对照组4例（8.33%）,但差异无统计学意义。结论珍珠明目滴眼液治疗慢性结膜炎效果确切,可改善患者相关症状,具有较高安全性。Objective To observe clinical effects of Zhenzhumingmu eye drops combing with antibiotic in treatment of chronic conjunctivitis.Methods 96 patients with chronic conjunctivitis from ophthalmology department from January 2015 to October 2016 were grouped two groups by draw method,each with 48 cases. The control group was treated with ofloxacin eye drops,and observation group was treated with Zhenzhumingmu eye drops combing with ofloxacin eye drops. Related indicators are analyzed in two groups. Results（1）Effective rate of observation group was 87. 50%,higher than control group with 66. 67%（ P〈 0. 05）.（2）Dry eye,eye itching,eye fatigue and foreign body sensation score of observation group were（ 1. 01 ± 0. 24）,（ 0. 93 ± 0. 22）,（ 0. 85 ± 0. 18）,（ 0. 81 ± 0. 25） points,lower than control group（ 1. 46 ± 0. 30）,（ 1. 39 ± 0. 25）,（ 1. 16 ± 0. 21）,（ 1. 22 ± 0. 29）（ all P〈 0. 05）.（3） Eye discomfort proportion of observation group was 12. 50%,higher than control group 8. 33%,but the difference was not statistically significant. Conclusion Zhenzhumingmu eye drops has exact curative effect in treatment of chronic conjunctivitis,can improve the symptoms and has high security.

关 键 词：珍珠明目滴眼液 氧氟沙星滴眼液 慢性结膜炎 

分 类 号：R777.31[医药卫生—眼科]