男性卒中后抑郁患者血清细胞因子水平变化分析  

作　　者：朱洁[1] 

机构地区：[1]重庆市急救医疗中心神经内科,重庆400016

出　　处：《中国药业》2016年第B12期64-65,共2页China Pharmaceuticals

摘　　要：目的分析血清细胞因子IL-6，hs-CRP，E2水平变化与男性脑卒中后抑郁的相关性。方法选取医院收治的脑梗死患者72例，36例脑梗死伴抑郁患者（对照组）采用酶联免疫吸附试验（ELISA）法，36例脑梗死后抑郁（研究组）患者采用放射免疫分析法，在脑梗死后第7，28天分别检测血清细胞因子IL-6，hs-CRP，E2水平。结果研究组患者第7，28天的血清IL-6和hs-CRP水平显著高于对照组，E2水平低于对照组。结论IL-6，hs-CRP，E2可能在男性脑卒中后抑郁患者的发病机理中起着重要作用。Objective To investigate the relationship of serum cell facto IL-6,HS-CRP,E2 and male depression after stroke. Methods The level of serum cell factor IL-6,HS-CRP,E2 of thirty-six patients who were cerebral infarction （control group） and depression after stroke （research group,n=36） respectively were examined by using enzyme linked immunosorbent assay and adioimmunoassay on 7th and 28th day after cerebral infarction.Results The level of serum cell factorIL-6,HS-CRP of research group （n=36） was higher than that of control group. The level of serum cell factor E2 of research group was lower than that of control group.Conclnsions Serum cell factorIL-6,HS-CRP,E2 may play an important role in pathogenic mechanism of male patients with poststroke depression.

关 键 词：卒中后抑郁 男性 雌激素 白细胞介素6 超敏C反应蛋白 

分 类 号：R749[医药卫生—神经病学与精神病学]