停戴角膜塑形镜期间角膜前表面形态恢复情况观察  

Recovery of anterior corneal biometry after discontinuation of orthokeratology

作　　者：周佳[1] 林伟平[1] 刘桂华[1] 李颖[1] 厉娜[1] 粘红[1] 魏瑞华[1] 

机构地区：[1]天津医科大学眼科医院,天津市300384

出　　处：《眼科新进展》2017年第8期739-742,共4页Recent Advances in Ophthalmology

基　　金：国家自然科学基金资助(编号:81570834)~~

摘　　要：目的观察不同屈光度患者配戴角膜塑形镜2 a后停戴不同时间角膜前表面形态的恢复情况。方法收集2012年10月至2014年10月在天津医科大学眼科医院近视防控门诊就诊且配戴角膜塑形镜2 a的8~14岁近视患者60例(60只右眼)进行自身对照研究。根据近视度数分为A组(等效球镜度数≤-2.00 D)、B组(等效球镜度数为>-2.00^-4.00 D)、C组(等效球镜度数为>-4.00^-6.00 D),分别在停戴角膜塑形镜1周、2周、1个月观察患者角膜前表面形态,包括平K值(FK值)、陡K值(SK值)和平均K值的恢复情况,同时观察眼轴长度以及中央角膜厚度的变化。结果A组角膜FK值、SK值、平均K值在停戴2周后与戴镜前相比差异均无统计学意义(均为P>0.05);B组角膜FK值、SK值、平均K值在停戴1个月后基本恢复至戴镜前水平;C组停戴1个月后FK值、SK值、平均K值与戴镜前相比,差异仍均有统计学意义(均为P<0.05)。3组中央角膜厚度在停戴2周后与戴镜前相比差异均无统计学意义(均为P>0.05)。B组与C组的眼轴长度,停戴2周与停戴1周相比差异均有统计学意义(均为P<0.05);3组停戴1个月与停戴2周相比差异均无统计学意义(均为P>0.05);停戴1个月后,A组、B组、C组眼轴长度较戴镜前分别增长了(0.43±0.36)mm、(0.35±0.21)mm和(0.36±0.29)mm。结论不同屈光度停戴后角膜参数恢复到戴镜前水平所需时间不同;短时间停戴未见眼轴长度明显增长。Objective To observe the short-term changes of anterior corneal biometry after discontinuation of orthokeratology in patients with 2-year wearing.Methods Retrospective study.Sixty myopic patients aged from 8-14 years old during October 2012 and October 2014 were wearing orthokeratology for 2 years in Tianjin Medical University Eye Hospital.According to the degree of myopia,they are divided into three groups（SE≤-2.00 D for group A,-2.00 D〈SE≤-4.00 D for group B and -4.00 D〈SE≤-6.00 D for group C）.The recovery of anterior corneal curvature,including flat K（FK）,steep K（SK）,average K （AVEK）,changes of axial length and central corneal thickness （CCT） at 1 week,2 weeks,1 month after discontinuation of orthokeratology were observed.Results There was no statistical differences in FK,SK,AVEK before and 2 weeks after wearing orthokeratology in group A （all P〉0.05）.While in group B,there was no significant difference in FK,SK,AVEK before and 1 month after wearing orthokeratology;There were statistically differences in FK,SK,AVEK at 1 month after discontinuation in group C compared with the baseline （all P〈0.05）.As for CCT,there was no statistical differences among group A,B,C after discontinuation of orthokeratology for 2 weeks （all P〉0.05）.There were statistical differences in the axial length between 1 week and 2 weeks after discontinuation of orthokeratology in group B and C （all P〈0.05）;There were statistical differences in the axial length between 1 month and 2 weeks after discontinuation of orthokeratology in three groups （all P〈0.05）;Compared with the state before wearing orthokeratology,the increase of axial length in group A,B,C were （0.43±0.36） mm,（0.35±0.21）mm and （0.36±0.29）mm,respectively.Conclusion The time course of returning to the original corneal parameter varies among different degree of myopia,and the axial length has no significant growth after short-term discontinuation.

关 键 词：角膜塑形镜 角膜曲率 角膜厚度 眼轴长度 

分 类 号：R778.1[医药卫生—眼科]