胃癌肝转移的手术治疗及预后分析  

Prognostic Analysis of Patients with Synchronous Liver Metastasis From Gastric Cancer Following Simultaneous Gastric and Liver Resection

作　　者：孙新增[1] 张霆[1] 白建平[1] 肖宝强 SUN Xinzeng ZHANG Ting BAI Jianping et al.(Department of General Surgery, No. 254 Hospital PLA , Tianj in City 300142)

机构地区：[1]中国人民解放军第二五四医院普通外科,天津市300142

出　　处：《医学理论与实践》2017年第13期1884-1885,1888,共3页The Journal of Medical Theory and Practice

摘　　要：目的:探讨胃癌肝转移的手术治疗效果及不同病理因素对预后的影响。方法:选取2000年1月-2016年1月我院普通外科收治的26例胃癌肝转移且行手术治疗的患者资料。对预后相关因素进行单因素与多因素分析。结果:胃癌肝转移手术切除后,5年生存率为11.5%。单因素分析结果显示,浆膜侵犯(P=0.046)、淋巴转移(P=0.046)、转移灶数目(P=0.046)、转移灶大小(P=0.019)、手术根治度(P=0.046)是影响患者预后的重要因素。多因素分析结果显示,浆膜侵犯、转移灶大小、转移灶数目是影响患者预后的独立性危险因素。结论:准确地掌握适应证,对于单发的直径<4cm的无浆膜侵犯胃癌肝转移患者,应积极手术切除,为患者争取更好的预后。Objective：To investigate the effect of surgical treatment on liver metastasis of gastric cancer and the effect of different pathological factors on the prognosis of gastric cancer.Methods：The data of 26 patients with liver metastasis of gastric cancer from January 2000 to January 2016 in our hospital were collected.Univariate and multivariate were used to analysis of prognostic factors.Results：The 5 years survival rate was 11.5% after resection of gastric cancer with liver metastasis.Univariate analysis revealed that Serous invasion（P=0.046）,lymphatic metastasis（P=0.046）,number of metastatic lesions（P=0.046）,metastatic lesion size（P=0.019）,radical degree of surgery（P=0.046）were important factors influencing the prognosis of patients with lymph node metastasis.Multivariate analysis revealed that serous invasion,metastatic lesion size,number of metastatic lesions were independent risk factors for patients.Conclusion：The prognosis of patients with gastric carcinoma with small diameter and small diameter can be improved by accurately grasping the indications.

关 键 词：胃肿瘤 肝转移 预后 

分 类 号：R735.2[医药卫生—肿瘤]