三维适形放疗联合EP方案治疗晚期胸腺癌的疗效分析  

Analysis Curative Effect of Three Dimensional Conformal Radiotherapy Combined With EP Regimen for Advanced Thymic Carcinoma

作　　者：徐宜全[1] 李莹莹[1] 卢其香 单秋洁 胡晓林[1] 杨冬[1] 

机构地区：[1]沭阳县人民医院肿瘤科,江苏宿迁223600

出　　处：《中国继续医学教育》2017年第16期176-177,共2页China Continuing Medical Education

摘　　要：目的观察三维适形放疗联合EP方案治疗晚期胸腺癌的临床效果。方法选取晚期胸腺癌患者50例,随机分为对照组(单纯三维适形放,n=25,)观察组(EP方案三周期后贯续三维适形放疗,n=25),比较两组患者治疗效果。结果观察组患者治疗总有效率为92.0%,对照组患者治疗总有效率为52%,组间比较差异有统计学意义(P<0.05);观察组患者的疾病控制率为95%,对照组患者的疾病控制率为80%,组间比较差异有统计学意义(P<0.05)。观察组患者不良反应发生率为16%,对照组患者不良反应发生率为20%,组间比较差异无统计学意义(P>0.05)。结论三维适形放疗联合EP方案治疗晚期胸腺癌较单纯放疗具有较好的临床效果。Objective To observe the clinical effect of three dimensional conformal radiotherapy combined with EP regimen in the treatment of advanced thymic carcinoma. Methods 50 patients with advanced thymic carcinoma were randomly divided into two groups： control group（simple three-dimensional conformal radiotherapy, n=25）, observation group（EP scheme, three cycles followed by three-dimensional conformal radiotherapy, n=25）, and the therapeutic effects of the two groups were compared. Results The total effective rate of the observation group was 92%, and the total effective rate of the control group was 52%, the difference between the two groups was statistically significant（P〈0.05）; The disease control rate of the observation group was 95%, and that of the control group was 80%, and the difference between the two groups was statistically significant（P〈0.05）. The incidence of adverse reactions was 16% in the observation group and 20% in the control group, and there was no significant difference between the two groups（P〉0.05）. Conclusion Three dimensional conformal radiation therapy combined with EP regimen in the treatment of advanced thymic carcinoma is better than radiotherapy alone.

关 键 词：胸腺癌 化疗 三维适形放疗 

分 类 号：R73[医药卫生—肿瘤]