β2-微球蛋白与缺血性卒中  

β2 -Microglobulin and ischemic stroke

作　　者：刘秋皖 群森[1] 吴竹青[1] 王小强[1] 吴君仓[1] Liu Qiuwan Qun Sen Wu Zhuqing Wang Xiaoqiang Wu Juncang(Department of Neurology, the Affiliated Hefei Hospital of Anhui Medical University, the Second People＇s Hospital of Hefei, Hefei 230011, China)

机构地区：[1]安徽医科大学附属合肥医院合肥市第二人民医院神经内科,230011

出　　处：《国际脑血管病杂志》2017年第6期536-540,共5页International Journal of Cerebrovascular Diseases

基　　金：合肥市卫生计生应用医学重点项目（合卫科教[2016]259号）

摘　　要：β2-微球蛋白是由一条肽链组成的小分子蛋白质。以往研究证实，血清β2-微球蛋白是一种反映早期肾功能损伤的生物标志物，而肾功能损伤与缺血性卒中之间关系密切。近年来的研究显示，缺血性卒中患者血清β2-微球蛋白水平明显增高，可作为缺血性卒中风险的生物标志物。β2-Microglobulin is a small molecule protein, consisting of a polypeptide chain. Previous studies have confirmed that serum β2-microglobulin is a biomarker that reflects early renal function injury, and renal function injury is closely correlated with ischemic stroke. Studies in recent years have shown that the level of serum β2-microglobulin increases significantly in patients with ischemic stroke. Thus, it can be used as a biomarker for the risk of ischemic stroke.

关 键 词：卒中 脑缺血 Β2-微球蛋白 炎症 肾功能不全 慢性 动脉粥样硬化 生物标志物 

分 类 号：R743.3[医药卫生—神经病学与精神病学]