法舒地尔联合血栓通治疗椎基底动脉供血不足性眩晕的疗效  

Effective observation of vertebrobasilar insufficiency vertigo treated with Fasudil and Xueshuantong injection

作　　者：杨玉佩[1] Yang Yupei(Department of Neurology, People ＇ s Hospital of Lushan, Lushan 467300, Chin)

机构地区：[1]鲁山县人民医院神经内科,河南鲁山467300

出　　处：《中国实用神经疾病杂志》2017年第14期34-35,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的观察法舒地尔联合血栓通治疗椎基底动脉供血不足性眩晕的效果。方法选取我院收治的椎基底动脉供血不足性眩晕患者156例为研究对象,采用随机对照分组法分为治疗组和对照组。治疗组78例给予法舒地尔30mg加入0.9%氯化钠注射液250mL静滴,1次/d,联合血栓通注射液300mg加入0.9%氯化钠注射液250mL静滴,1次/d。对照组给予培他啶注射液500mL静滴,1次/d,联合血栓通注射液300mg加入0.9%氯化钠注射液250mL静滴,1次/d。2组疗程均为14d,观察比较2组临床疗效及不良反应。结果治疗组显效率87.18%,好转率15.38%,总有效率98.72%,对照组显效率66.67%,好转率29.49%,总有效率96.15%,2组总有效率比较差异无统计学意义(P>0.05),治疗组显效率优于对照组,差异有统计学意义(P<0.05)。2组均未出现明显不良反应。结论法舒地尔联合血栓通治疗椎基底动脉供血不足性眩晕效果确切,安全可靠,值得临床推广。Objective To observe the effect of Fasudil combined with Xueshuantong injection in the treatment of verte- brobasilar insufficiency vertigo. Methods One hundred and fifty-six patients with vertebrabasilar insufficiency vertigo in our hos pital were recruited and randomly divided into treatment group and control group. Seventy-eight patients in treatment group were treated with Fasudil Hydrochloride 30 mg added in 250 mL 0.9% sodium chloride injection,intravenous infusion,one time a day; Xueshuantong injection 300 mg added in 250 mL 0.9% sodium chloride injection,intravenous infusion, one time a day. Seventy- eight patients in control group were treated with Betahistine Hydrochloride 500 mL, intravenous infusion, one time a day; Xue shuantong injection 300 mg added in 0.9 % sodium chloride injection 250 mL, intravenous infusion, one time a day. Two groups were treated for 14 day,and the clinical curative effect and adverse reactions were compared. Results In the treatment group,the significant efficiency was 87.18 %,the improvement rate was 15.38%,and the total efficiency was 98.72 %. In the control group, the significant efficiency was 66.67 %, the improvement rate was 29.49 % ,and the total efficiency was 96.15 %. There as no statis- tical significance on the total efficiency in the two groups （P〈0.05）. The significant efficiency and the improvement rate of treat ment group were better than those of the control group,the differences were statistically significant （P〈0.05）. There were no ob viously adverse reactions in the two groups. Conclusion The effect of vertebrobasilar insufficiency vertigo treated with Fasudil and Xueshuantong is exact, safe and reliable,which is worth of promoting.

关 键 词：眩晕 椎基底动脉供血不足 法舒地尔 

分 类 号：R743[医药卫生—神经病学与精神病学]