纳米炭淋巴结示踪剂在腔镜食管癌根治术中的应用  

Application of nano-carbon lymph node tracer in radical resection of esophageal cancer by VATS

作　　者：黎佩建[1] 魏崴[1] 李勇生[1] 钟标[1] 

机构地区：[1]惠州市中心人民医院胸心外科,广东惠州516000

出　　处：《现代肿瘤医学》2017年第17期2755-2757,共3页Journal of Modern Oncology

摘　　要：目的:探讨纳米炭淋巴结示踪剂在腔镜食管癌根治术中的应用效果。方法:选行腔镜食管癌切除患者46例,按随机数字表法分为观察组和对照组,各23例。观察组术前2 h胃镜下注射纳米炭淋巴结示踪剂;对照组不给示踪剂,对比两组的淋巴结清扫数目、淋巴结黑染率及术后6个月内并发症。结果:观察组平均清扫淋巴结数、<5 mm淋巴结及其转移明显高于对照组;淋巴结清扫时间和平均最小淋巴结直径均明显低于对照组,差异具有统计学意义(P<0.05);观察组淋巴结黑染率明显高于对照组,且黑染淋巴结的转移度明显高于非黑染者(P<0.01);观察组术中出血量、术后引流量、喉返神经损伤发生率明显低于对照组(P<0.05)。结论:纳米炭示踪剂在腔镜食管癌根治术中有助于淋巴检出、缩短检出时间、提高转移淋巴结检出度,以及小淋巴结的检出,降低术中喉返神经损伤。Objective To investigate the clinical effect of nano - carbon tracer in the dissection of lymph node un-der video assisted thoracic surgery（ VATS）. Methods ：Totally 46 patients with esophageal cancer were randomly di-vided into two groups 23 in each. In the observation group,the carbon lymph tracer was injected into submucous under gastroscopy 2 h before operation,the control group without. The black dyed lymph nodes,number of dissected lymph nodes,metastasis rate, intra and post operative bleeding as well as complications were compared between the two groups. Results：The average number of lymph nodes, 〈5 mm lymph nodes and metastasis lymph nodes in observation group were significantly higher than that of control group （P 〈0. 05） . The time of dissection of lymph nodes and the average diameter of the minimum lymph nodes were significantly less than that of control （ P 〈 0. 01） . The blood loss, the postoperative drainage and recurrent laryngeal nerve injury in observation group were significantly lower than that of control either（ P 〈 0. 05 ） . Conclusion ： Nano - carbon tracer is helpful to detect and dissect the metastasis lymph nodes during esophageal carcinoma radical resectionby VATS.

关 键 词：纳米炭淋巴结示踪剂 食管癌 电视辅助胸腔镜手术 喉返神经 淋巴结清扫术 

分 类 号：R735.1[医药卫生—肿瘤]