第四脑室室管膜瘤的临床特点和治疗(附19例临床分析)  

Clinical features and treatmentsof ependymomas in the fourth ventricle: report of 19 cases

作　　者：夏养华 程传东 费小瑞 董永飞 汪业汉 

机构地区：[1]安徽医科大学附属省立医院神经外科,脑功能与脑疾病安徽省重点实验室,合肥市230001

出　　处：《立体定向和功能性神经外科杂志》2017年第2期86-89,共4页Chinese Journal of Stereotactic and Functional Neurosurgery

基　　金：安徽省自然科学青年基金项目(编号:1508085QH184)

摘　　要：目的探讨第四脑室室管膜瘤的临床特点和治疗方法。方法回顾性分析2011年1月至2015年12月安徽省立医院收治的19例第四脑室室管膜瘤患者的临床特点、治疗和预后。结果首发症状多为头痛、呕吐等高颅压症状,常伴有梗阻性脑积水。本组患者肿瘤全切除12例,次全切除4例,大部切除2例,部分切除1例。无手术死亡病例。术后接受放疗9例,3例还接受了化疗。术后随访16例,平均随访36.2个月,复发5例,再次手术2例,死亡4例。结论第四脑室室管膜瘤容易复发,治疗应采用手术联合放疗。复发患者可再次手术。Objective To explore the clinical features and treatments of ependymomas in the fourth ventricle. Methods The clinical features,treatments and prognosis of 19 patients with ependymomas in the fourth ventricletreated in our hospital from January 2011 to December 2015 wereanalyzed retrospectively. Results The first symptom is headache,vomiting and other high intracranial pressure symptoms,often accompanied by obstructive hydrocephalus. 12 patients received total removal of the tumors,4 subtotal removal,2 gross removal and 1 partial removal. No operative death occurred. 9 receivedpostoperative radiotherapy,3 also received chemotherapy. Sixteenpatients were followed-upmean 36. 2 months. 5 patientsdeveloped tumor local recurrence and 2 received reoperations. 4 patients died. Conclusion Ependymomas in the fourth ventricleare prone to local recurrence. Treatment of the tumor should be the combination ofsurgery and radiotherapy. Recurrent patients can perform reoperations.

关 键 词：室管膜瘤 第四脑室 治疗 

分 类 号：R739.41[医药卫生—肿瘤]