同时诊断慢性淋巴细胞白血病及恶性实体瘤2例  

Two cases of simultaneous diagnosis of chronic lymphocytic leukemia and solid maligant neoplasm

作　　者：王丹[1] 陈昀[1] 郭农建[1] 

机构地区：[1]山东大学附属济南市中心医院血液科,济南250013

出　　处：《临床血液学杂志》2017年第4期551-554,共4页Journal of Clinical Hematology

摘　　要：近年来随着新药的应用,慢性淋巴细胞白血病（chronic lymphocytic leukemia,CLL）预后得到改善,生存期得到延长,有关CLL合并第二肿瘤国内外报道日益增多,但多为异时性,同时诊断CLL及非血液系统恶性肿瘤的病例临床少见。我院近期收治2例同时诊断CLL和实体瘤2种恶性肿瘤的患者,现将该病例报告如下。Chronic lymphocytic leukemia（CLL）is a kind of indolent lymphoma originated from B cell.In western countries,CLL is one of the most common types of adult leukemia,but in our country and other Asian region,the incidence of CLL is relatively low.What＇s more,diagnosed with CLL and other non blood system solid malignant neoplasm at the same time is rare in clinic.Our hospital recently admitted 2patients who had been diagnosed with CLL and malignant neoplasm at the same time.The occurrence of the second neoplasm in addition to be linked to the treatment of primary neoplasm,it was also linked to biological factors,the body＇s genetic background and immune abnormalities.The treatment should follow two lines,including comprehensive treatment and individualized treatment.

关 键 词：同时诊断 白血病 淋巴细胞 慢性 恶性实体瘤 

分 类 号：R733[医药卫生—肿瘤]