群体抗癌对晚期肿瘤患者心理状态及生活质量的影响  

The effect of group anti-cancer pattern on psychological status and quality of life in patients with advanced cancer

作　　者：陈彩霞 郝睿楠 郭欣 

机构地区：[1]郑州市人民医院,河南郑州450000

出　　处：《临床心身疾病杂志》2017年第4期91-95,共5页Journal of Clinical Psychosomatic Diseases

基　　金：郑州市2015年度科技发展计划项目（编号20150071）

摘　　要：目的探讨群体抗癌对晚期肿瘤患者心理状态及生活质量的影响。方法将100例晚期肿瘤患者按照随机数字表法分为两组，每组50例。两组均接受常规治疗及护理，观察组在此基础上联合群体抗癌活动，随访12个月。采用焦虑自评量表、抑郁自评量表及癌症生命质量核心量表评定心理状态及生活质量，并检测外周血T淋巴细胞亚群水平变化，采用满意度测评量表调查患者满意度。结果人院时两组各量表评分及各项免疫指标检测结果比较差异无统计学意义（P〉0．01），随访6个月及12个月两组均较入院时有显著改善（P〈0．01）。随访6个月及12个月，观察组焦虑自评量表及抑郁自评量表评分均显著低于对照组（P〈0．01）；癌症生命质量核心量表的功能领域、健康状况领域评分均显著高于对照组（P〈0．01），症状领域评分显著低于对照组（P〈0．01）；CD3＋、CD4＋、CD4＋／CD8＋水平均显著高于对照组（P〈0．01），CD8＋水平显著低于对照组（P〈0．01）。随访12个月，观察组满意率为96．0％，对照组为82．0％，观察组显著高于对照组（P〈0．05）。结论群体抗癌可显著消除晚期肿瘤患者的不良情绪，提高其生活质量，改善机体免疫功能，增加患者满意度。Objective To study the influence of group anti-cancer pattern to psychological status and quali- ty of life in patients with advanced cancer. Methods According to the random number table method, 100 cases of advanced cancer patients treated in our hospital from May 2014 to June 2015 were divided into observation group and control group, 50 cases in each group. Patients in both group were given routine treatment, while the observation group was combined with group anti-cancer activity, follow-up of 12 months. By the self rating Anxiety Scale （SAS）, self rating Depression Scale （SDS） and QLQ-30 （V3.0） questionnaire to assess the psychological status and quality of life, and uses the detection level of peripheral blood T lymphocyte subsets changes, adopts the satisfaction scale survey patients＇ satisfaction. Results Compared with admission, the rating scale and the immune indexes comparison test results of two groups has no statistical significant difference （P〉0.01）. Followed up for 6 months and 1 year SAS, SDS scores of observation group were significantly lower than control group. Core scale cancer quality of life of function areas, health scores were significantly higher than that of control group （P〈0.01）, the symptoms score was significantly lower than control group （P〈 0.01）. Observation group＇ s CD3＋ , CD4＋ 、 CD4＋/CD8＋ levels were significantly higher than that of control group, and CD8＋ were significantly lower than the control group. After 1 years follow-up, the satisfaction of observation group was 96.00%, significantly high- er than that of control group 82.00%（P〈0.05）. Conclusion Group anticancer model applied in advanced cancer patients can significantly eliminate the patients unhealthy emotions, improve the quality of life and the body＇s immune function and increase patient satisfaction.

关 键 词：晚期肿瘤 群体抗癌模式 心理状态 生活质量 免疫功能 

分 类 号：R73[医药卫生—肿瘤]