液体石蜡对粘连性小肠梗阻的干预作用  

Intervention effects of fluid wax on adhesive small bowel obstruction

作　　者：吴小昌[1] 袁玉梅[2] 谢平[1] 钱海[1] 

机构地区：[1]湖州市中心医院胃肠外科,浙江湖州313000 [2]湖州市中心医院临床药学科,浙江湖州313000

出　　处：《中国中西医结合急救杂志》2017年第4期423-425,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：浙江省医药卫生一般研究计划项目（2015KYB374）

摘　　要：目的 观察液体石蜡在粘连性小肠梗阻病程中的干预作用.方法 选择湖州中心医院胃肠外科2014年12月至2016年6月收治的粘连性肠梗阻患者288例,按机械抽样法分为液体石蜡组和对照组,每组144例.对照组采用传统综合非手术治疗,胃肠减压2 h后,液体石蜡组经胃管注入液体石蜡3 mL/kg,夹闭胃管2 h.观察两组治疗后第1次排气时间、第1次排便时间、腹痛缓解时间、气液平消失时间、住院时间、手术率和不良反应发生情况.结果 治疗后液体石蜡组第1次排气时间、第1次排便时间、腹痛缓解时间、气液平消失时间、住院时间均较对照组明显缩短〔第1次排气时间（h）：29.97±19.71比49.28±33.61,第1次排便时间（h）：60.25±28.37比74.23±50.12,腹痛缓解时间（h）：35.78±20.98比51.83±25.02,气液平消失时间（h）：71.60±39.50比90.98±57.91,住院时间（d）：7.00±3.77比9.00±5.81,均P〈0.05〕,手术率较对照组明显降低〔18.75%（27/144）比27.08%（39/144）,P〈0.05〕.两组均无死亡病例.随访近1年液体石蜡组未见与研究相关的不良反应.结论 液体石蜡联合传统非手术方法干预可明显缩短粘连性肠梗阻患者病程时间,降低手术率,减少住院时间.Objective To observe the intervention effects of fluid wax on the therapeutic course of patients with adhesive small bowel obstruction.Methods Two hundreds and eighty-eight patients with adhesive small bowel obstruction admitted into the Department of Gastrointestinal Surgery of Huzhou Central Hospital from December 2014 to June 2016 were enrolled, and they were divided into a fluid wax group and acontrol group by mechanical sampling method, each group 144 cases. The control group was treated with conventional comprehensive non-surgical treatment, in the fluid wax group, on the basis of the above conventional treatment, additionally after 2 hours of gastrointestinal decompression, the fluid wax 3 mL/kg was injected through a gastric tube that then was closed by a clip for 2 hours. The first exhaust and defecation times, the time for amelioration of abdominal pain, the time of gas-liquid flat disappearance, the length of stay in hospital, the rate of operation and the occurrence of adverse reactions were observed in the two groups.Results After treatment, the first exhaust time, the first defecation time, the time of relieving abdominal pain, the time of gas-liquid flat disappearance and the length of stay in hospital were significantly shorter in fluid wax group than those in control group [the first exhaust time （hours）： 29.97±19.71 vs. 49.28±33.61, the first defecation time （hours）： 60.25±28.37 vs.74.23±50.12, the time of relieving abdominal pain （hours）： 35.78±20.98 vs. 51.83±25.02, the time of gas-liquid flat disappearance （hours）： 71.60±39.50 vs. 90.98±57.91, the length of stay in hospital （days）： 7.00±3.77 vs. 9.00±5.81, allP 〈 0.05], and the rate of operation in the fluid wax group was lower than that in the control group [18.75% （27/144） vs. 27.08% （39/144）,P 〈 0.05]. No patients died in the two groups. In nearly 1 year follow-up, there were no adverse reactions associated with the study in the fluid wax group.Conclusion The intervention of fluid wax com

关 键 词：粘连性小肠梗阻 液体石蜡 疗效 

分 类 号：R574.2[医药卫生—消化系统]