注射用还原型谷胱甘肽治疗中重度非酒精性脂肪肝的临床疗效观察  

Clinical Observation of Restorative Glutathione in the Treatment of Moderate to Severe Nonalcoholic Fatty Liver Disease

作　　者：邢诗敏 

机构地区：[1]大连港医院药剂科,辽宁大连116015

出　　处：《中国医药指南》2017年第22期45-46,共2页Guide of China Medicine

摘　　要：目的探讨注射用还原型谷胱甘肽治疗中重度非酒精性脂肪肝的临床疗效。方法选取2015年6月至2016年6月在大连港医院就诊的非酒精性脂肪肝患者30例,随机分为试验组和对照组,试验组15例,采取注射用还原型谷胱甘肽治疗,对照组15例,给予甘草酸二铵注射液治疗。比较两组患者的肝酶指标。结果试验组与对照组在治疗前ALT、AST、GGT、ALP比较没有统计学差异(P>0.05);治疗后组间比较试验组ALT、AST、GGT、ALP均优于对照组,差异有统计学差异(P<0.05)。结论注射用还原型谷胱甘肽治疗中重度非酒精性脂肪肝效果显著,可以明显改善患者的肝功情况。Objective To study the reduced glutathione for injection in the treatment of moderately severe nonalcoholic fatty liver disease in the clinical curative effect..Methods In June 2015 to June 2016 in Dalian hospital of 30 patients with nonalcoholic fatty liver disease, were randomly divided into experimental group and control group, experimental group, 15 cases treated with reduced glutathione for injection, the control group, 15 cases give two ammonium glyeyrrhetate injection treatment. Comparison of two groups of patients with liver enzyme indicators. Results The experimental group and control group before treatment ofALT, AST, GGT and ALP is no statistical difference （P〉0.05）; after treatment group comparison between experimental group ALT, AST, GGT and ALP were superior to control group, the difference was statistically difference （P〈0.05）. Conclusion Reduced glutathione for injection in the treatment of moderately severe nonalcoholic fatty liver disease effect significantly, can significantly improve the patient＇s liver result.

关 键 词：注射用还原型谷胱甘肽 甘草酸二铵注射液 中重度非酒精性脂肪肝 

分 类 号：R575.5[医药卫生—消化系统]